Evidence map›Paper›PMID 29127419›Full record

Trial reportScientific reports2017

Bacteremic and non-bacteremic pneumonia caused by Acinetobacter baumannii in ICUs of South China: A Clinical and Microbiological Study.

Yunfang Tan, Kai Zhou, Xiang Tang, Timothy Kudinha, Luxia Wang, Zhenghui Guo, Murat Akova, Chao Zhuo

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  8. Determinants of Mortality in Patients with NosocomialThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Yunfang TanState Key Laboratory of Respiratory Diseases, the first affiliated hospital of Guangzhou Medical College, Guangzhou, China.
Kai ZhouState Key Laboratory for Diagnosis and Treatment of Infectious Diseases; Collaborative. Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated. Hospital of Medicine School, Zhejiang University, Hangzhou, China.
Xiang TangState Key Laboratory of Respiratory Diseases, the first affiliated hospital of Guangzhou Medical College, Guangzhou, China.
Timothy KudinhaCharles Sturt University, Leeds Parade, Orange, New South Wales, Australia.
Luxia WangGuangzhou general hospital of Guangzhou Military, Guangzhou, China.
Zhenghui GuoGuangzhou general hospital of Guangzhou Military, Guangzhou, China.
Murat AkovaHacettepe University School of Medicine, Department of Infectious Disease, Ankara, 06100, Turkey. makova@hacettepe.edu.tr.
Chao ZhuoState Key Laboratory of Respiratory Diseases, the first affiliated hospital of Guangzhou Medical College, Guangzhou, China. chao_sheep@263.net.ORCID 0000-0002-3640-6518
General Hospital of Guangzhou Military Command · CNState Key Laboratory of Respiratory Disease · CNCharles Sturt University · AUFirst Affiliated Hospital of Guangzhou Medical University · CNFirst Affiliated Hospital Zhejiang University · CNHacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acinetobacter baumannii has been a dreadful problem for ICU physicians for a long time. Bacteremic pneumonia (BP) caused by this organism has a higher mortality compared to other organisms. Between 2012 and 2015, 86 BP and 89 non-bacteremic pneumonia (NBP) patients from five ICUs were enrolled into the study. The 7-day and 14-day mortality rates were higher in BP patients than in NBP patients (P < 0.001). Procalcitonin elevation, high APACHEII score and recent surgery, were independently associated with BP episodes. Acute respiratory distress syndrome, coma, high APACHEII score and procalcitonin elevation, were independently associated with mortality in the BP group. Extensively drug-resistant isolates were detected in 34.9% of BP and 25.8% of NBP isolates. PFGE identified 12 and 9 genotypes in the BP and NBP isolates, respectively, with 6 genotypes shared by both groups. ST195 was the most prevalent type (40%), followed by ST457 (18.9%). The pandemic clonal complex 92 was predominant, accounting for 94.3% of the strains. For all studied periods, mortality remained higher in the BP than the NBP group. Disease severity was the main risk factor for high mortality in the BP group, and other factors related to mortality were infection, and not treatment or microbiology-related.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsBacteremiaDrug Resistance, BacterialIntensive Care UnitsPneumonia, BacterialRespiratory Distress SyndromeAgedAged, 80 and overChinaFemaleHumansMaleMiddle AgedPrevalence

Identifiers

PMID29127419
PMCPMC5681499
OpenAlexW2767943199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.