Evidence map›Paper›PMID 29127352›Full record

ArticleScientific reports2017

Margination of Stiffened Red Blood Cells Regulated By Vessel Geometry.

Yuanyuan Chen, Donghai Li, Yongjian Li, Jiandi Wan, Jiang Li, Haosheng Chen

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuanyuan ChenState Key Laboratory of Tribology, Tsinghua University, Beijing, 100084, China.ORCID 0000-0003-2452-4725
Donghai LiState Key Laboratory of Tribology, Tsinghua University, Beijing, 100084, China.
Yongjian LiState Key Laboratory of Tribology, Tsinghua University, Beijing, 100084, China.
Jiandi WanDepartment of Microsystem Engineering, Rochester Institute of Technology, Rochester, NY, 14623, USA.
Jiang LiSchool of Mechanical Engineering, University of Science and Technology Beijing, Beijing, 100083, China.ORCID 0000-0001-5443-5550
Haosheng ChenState Key Laboratory of Tribology, Tsinghua University, Beijing, 100084, China. chenhs@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Margination of stiffened red blood cells has been implicated in many vascular diseases. Here, we report the margination of stiffened RBCs in vivo, and reveal the crucial role of the vessel geometry in the margination by calculations when the blood is seen as viscoelastic fluid. The vessel-geometry-regulated margination is then confirmed by in vitro experiments in microfluidic devices, and it establishes new insights to cell sorting technology and artificial blood vessel fabrication.

Indexed as

MicrocirculationMicrofluidic Analytical TechniquesModels, CardiovascularAnimalsErythrocytesMice

Identifiers

PMID29127352
PMCPMC5681636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.