Evidence map›Paper›PMID 29127232›Full record

ArticleBMJ open2017

Epidemiology of hypertension in Northern Tanzania: a community-based mixed-methods study.

Sophie W Galson, Catherine A Staton, Francis Karia, Kajiru Kilonzo, Joseph Lunyera, Uptal D Patel, Julian T Hertz, John W Stanifer

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In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sophie W GalsonDivision of Emergency Medicine, Department of Surgery, Duke University, Durham, North Carolina, USA.
Catherine A StatonDivision of Emergency Medicine, Department of Surgery, Duke University, Durham, North Carolina, USA.
Francis KariaKilimanjaro Christian Medical University College, Moshi, Tanzania.
Kajiru KilonzoDepartment of Medicine, Kilimanjaro Christian Medical Center, Moshi, Tanzania.
Joseph LunyeraDivision of General Internal Medicine, Department of Medicine, Duke University, Durham, North Carolina, USA.
Uptal D PatelDepartment of Medicine, Duke Clinical Research Institute , Duke University, Durham, North Carolina, USA.
Julian T HertzDivision of Emergency Medicine, Department of Surgery, Duke University, Durham, North Carolina, USA.
John W StaniferDuke Global Health Institute, Durham, North Carolina, USA.

Funding

Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Addressing High Risk Alcohol Use Amongst Injury Patients in an Emergency Department in TanzaniaK01TW010000 · FIC · DUKE UNIVERSITY · PI STATON, CATHERINE ANN · 2015 to 2018
$477k
FIC NIH HHS K01 TW010000FIC NIH HHS R25 TW009337
6 · The paper itself

Abstract

introductionSub-Saharan Africa is particularly vulnerable to the growing global burden of hypertension, but epidemiological studies are limited and barriers to optimal management are poorly understood. Therefore, we undertook a community-based mixed-methods study in Tanzania to investigate the epidemiology of hypertension and barriers to care.

methodsIn Northern Tanzania, between December 2013 and June 2015, we conducted a mixed-methods study, including a cross-sectional household epidemiological survey and qualitative sessions of focus groups and in-depth interviews. For the survey, we assessed for hypertension, defined as a single blood pressure ≥160/100 mm Hg, a two-time average of ≥140/90 mm Hg or current use of antihypertensive medications. To investigate relationships with potential risk factors, we used adjusted generalised linear models. Uncontrolled hypertension was defined as a two-time average measurement of ≥160/100 mm Hg irrespective of treatment status. Hypertension awareness was defined as a self-reported disease history in a participant with confirmed hypertension. To explore barriers to care, we identified emerging themes using an inductive approach within the framework method.

resultsWe enrolled 481 adults (median age 45 years) from 346 households, including 123 men (25.6%) and 358 women (74.4%). Overall, the prevalence of hypertension was 28.0% (95% CI 19.4% to 38.7%), which was independently associated with age >60 years (prevalence risk ratio (PRR) 4.68; 95% CI 2.25 to 9.74) and alcohol use (PRR 1.72; 95% CI 1.15 to 2.58). Traditional medicine use was inversely associated with hypertension (PRR 0.37; 95% CI 0.26 to 0.54). Nearly half (48.3%) of the participants were aware of their disease, but almost all (95.3%) had uncontrolled hypertension. In the qualitative sessions, we identified barriers to optimal care, including poor point-of-care communication, poor understanding of hypertension and structural barriers such as long wait times and undertrained providers.

conclusionsIn Northern Tanzania, the burden of hypertensive disease is substantial, and optimal hypertension control is rare. Transdisciplinary strategies sensitive to local practices should be explored to facilitate early diagnosis and sustained care delivery.

Indexed as

HypertensionAdultAntihypertensive AgentsBlood Pressure DeterminationCross-Sectional StudiesFemaleHumansMaleMedicine, TraditionalMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesTanzaniaAntihypertensive AgentsHealth DisparitiesHypertensionNon-communicable diseasesQualitative research

Identifiers

PMID29127232
PMCPMC5695455

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.