Evidence map›Paper›PMID 29126930›Full record

ArticleBehavioural brain research2018

White matter integrity mediates decline in age-related inhibitory control.

Peipei Li, Angeliki Tsapanou, Razlighi R Qolamreza, Yunglin Gazes

Abstract read
In one paragraph

Article in Behavioural brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peipei LiCognitive Neuroscience Division, Department of Neurology, Columbia University Medical Center, 630 W168th Street, P&S Box 16, New York, NY 10032, United States. Electronic address: pl2549@cumc.columbia.edu.
Angeliki TsapanouCognitive Neuroscience Division, Department of Neurology, Columbia University Medical Center, 630 W168th Street, P&S Box 16, New York, NY 10032, United States. Electronic address: at2859@cumc.columbia.edu.
Razlighi R QolamrezaCognitive Neuroscience Division, Department of Neurology, Columbia University Medical Center, 630 W168th Street, P&S Box 16, New York, NY 10032, United States. Electronic address: qr2108@cumc.columbia.edu.
Yunglin GazesCognitive Neuroscience Division, Department of Neurology, Columbia University Medical Center, 630 W168th Street, P&S Box 16, New York, NY 10032, United States. Electronic address: yl2107@cumc.columbia.edu.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
Exploring Cognitive Aging Using Reference Ability Neural NetworksR01AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2011 to 2025
$17.0M
Imaging of Cognition, Learning and Memory in AgingR01AG026158 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2004 to 2021
$10.9M
Exploring Cognitive Aging Using Refernce Ability Neural NetworksRF1AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2016 to 2018
$7.6M
Longitudinal changes in white matter integrity predicting cognitive changes in reasoning and vocabulary abilitiesK01AG051777 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAZES, YUNGLIN · 2016 to 2020
$623k
NCRR NIH HHS UL1 RR024156NIA NIH HHS K01 AG051777NIA NIH HHS R01 AG026158NIA NIH HHS R01 AG038465NIA NIH HHS RF1 AG038465
6 · The paper itself

Abstract

Previous DTI studies have reported associations between white matter integrity and performance on the Stroop interference task. The current study aimed to add to these studies of inhibitory control by investigating how the differences in age and in white matter integrity relate to Stroop performance, and to examine whether the effect of age on Stroop performance is mediated by white matter integrity. 179 healthy adults from 20 to 80 years old were recruited in the study. DTI data were processed through TRACULA and the mean fractional anisotropy (FA) of 18 major white matter tracts were extracted and used for statistical analysis. Correlation analysis showed a strong negative relationship between age and the Stroop interference score (I

Indexed as

AgingAnisotropyBrainCognitionDiffusion Tensor ImagingFemaleHumansMalePyramidal TractsSynaptic TransmissionWhite MatterAgingDTIInhibitory controlMediation effectStroop interferenceWhite matter integrity

Identifiers

PMID29126930
PMCPMC5729101

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.