Evidence map›Paper›PMID 29126597›Full record

ReviewMolecular immunology2019

Role of autophagy in MHC class I-restricted antigen presentation.

Luc Van Kaer, Vrajesh V Parekh, J Luke Postoak, Lan Wu

Abstract readReview
In one paragraph

Review in Molecular immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Stat3-mediated Atg7 expression enhances anti-tumor immunity in melanoma.bioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. Breaking the cellular defense: the role of autophagy evasion inFrontiers in cellular and infection microbiology · 2024
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Self-adjuvanting cancer nanovaccines.Journal of nanobiotechnology · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luc Van KaerDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Electronic address: luc.van.kaer@vanderbilt.edu.
Vrajesh V ParekhDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
J Luke PostoakDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Lan WuDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4M
Immunobiology of Blood and Vascular Systems Training ProgramT32HL069765 · NHLBI · VANDERBILT UNIVERSITY · PI HAWIGER, JACK J · 2002 to 2016
$6.5M
Interdisciplinary Training in Rheumatic DiseasesT32AR059039 · NIAMS · VANDERBILT UNIVERSITY · PI Tracy Minan Frech, AMY S MAJOR · 2010 to 2026
$4.3M
Role of autophagy-related protein Vps34 in antigen presentation and self-toleranceR01AI139046 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN KAER, LUC · 2019 to 2023
$2.2M
Mechanisms and consequences of iNKT cell anergyR01AI070305 · NIAID · VANDERBILT UNIVERSITY · PI VAN KAER, LUC · 2007 to 2011
$1.9M
Glycolipid-Reactive NKT Cells, Obesity and Insulin ResistanceR01DK081536 · NIDDK · VANDERBILT UNIVERSITY · PI VAN KAER, LUC, WU, LAN · 2010 to 2013
$1.3M
iCD8alpha cells as novel innate-type lymphoid cells that mediate gut immunityR01DK104817 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN KAER, LUC · 2015 to 2018
$1.3M
NHLBI NIH HHS T32 HL069765NIAID NIH HHS R01 AI070305NIAID NIH HHS R01 AI139046NIAMS NIH HHS T32 AR059039NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK081536NIDDK NIH HHS R01 DK104817NIGMS NIH HHS R25 GM062459
6 · The paper itself

Abstract

Major histocompatibility complex (MHC) class I molecules present peptide antigens to MHC class I-restricted CD8

Indexed as

AnimalsAntigen PresentationAutophagyCD8-Positive T-LymphocytesCross-PrimingHistocompatibility Antigens Class IHumansLysosomesHistocompatibility Antigens Class IAntigen presentationAutophagyAutophagy-related proteinsCD8(+) T cellsMHC class IVps34

Identifiers

PMID29126597
PMCPMC5940586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.