Evidence map›Paper›PMID 29126255›Full record

SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Economic Evaluations of Mass Drug Administration: The Importance of Economies of Scale and Scope.

Hugo C Turner, Jaspreet Toor, T Déirdre Hollingsworth, Roy M Anderson

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
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  7. Article
  8. Article
  9. Article
  10. An Updated Economic Assessment of Moxidectin Treatment Strategies for Onchocerciasis Elimination.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  11. Article
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  13. Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies.The journal of venomous animals and toxins including tropical diseases · 2023
    Article
  14. Article
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  17. Review
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  20. Optimizing the Number of Child Deaths Averted with Mass Azithromycin Distribution.The American journal of tropical medicine and hygiene · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hugo C TurnerOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Jaspreet ToorLondon Centre for Neglected Tropical Disease Research, University of Oxford, United Kingdom.
T Déirdre HollingsworthMathematics Institute, University of Oxford, United Kingdom.
Roy M AndersonLondon Centre for Neglected Tropical Disease Research, University of Oxford, United Kingdom.

Funding

Medical Research Council MR/R015600/1Wellcome Trust 089276/B/09/7
6 · The paper itself

Abstract

It is recognized that changing the current approaches for the control of the neglected tropical diseases will be needed to reach the World Health Organization's (WHO) 2020 goals. Consequently, it is important that economic evaluations of the alternative approaches are conducted. A vital component of such evaluations is the issue of how the intervention's costs should be incorporated. We discuss this issue-focusing on mass drug administration. We argue that the common approach of assuming an intervention's cost per treatment is constant, regardless of the number of individuals treated, is a misleading way to consider the delivery costs of mass drug administration due to the occurrence of economies/diseconomies of scale and scope. Greater care and consideration are required when the costs are incorporated into such analyses. Without this, these economic evaluations could potentially lead to incorrect policy recommendations.

Indexed as

Mass Drug AdministrationCost-Benefit AnalysisDrug CostsHumansWorld Health Organization

Identifiers

PMID29126255
PMCPMC5888956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.