ArticleBioinformatics (Oxford, England)2018
Complex analyses of inverted repeats in mitochondrial genomes revealed their importance and variability.
Article in Bioinformatics (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 37 citations in OpenAlex.
- Characterization of Hairpin Loops and Cruciforms Across 118,019 Genomes Spanning the Tree of Life.Genome biology and evolution · 2026Article
- Small but mighty: mitochondrial DNA at the centre of retrograde signalling.Cell communication and signaling : CCS · 2026Review
- Assembly and comparative analysis of the complete mitochondrial genome ofFrontiers in plant science · 2026Article
- De novo assembly of the mitochondrial genome of Glycyrrhiza glabra and identification of two types of homologous recombination configurations caused by repeat sequences.BMC genomics · 2025Article
- Phylogenetic classification and genetic insights from the complete mitochondrial genome ofFrontiers in plant science · 2025Article
- Evolution of Repetitive Elements, Their Roles in Homeostasis and Human Disease, and Potential Therapeutic Applications.Biomolecules · 2024Review
- Characterization of the Complete Mitochondrial Genome of Wintersweet (Life (Basel, Switzerland) · 2024Article
- Variability of Inverted Repeats in All Available Genomes of Bacteria.Microbiology spectrum · 2023Article
- Variation in Rice Plastid Genomes in Wide Crossing Reveals Dynamic Nucleo-Cytoplasmic Interaction.Genes · 2023Article
- The mitochondrial genome of the bioluminescent fishZooKeys · 2023Article
- Beyond the Primary Structure of Nucleic Acids: Potential Roles of Epigenetics and Noncanonical Structures in the Regulations of Plant Growth and Stress Responses.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Interaction of Proteins with Inverted Repeats and Cruciform Structures in Nucleic Acids.International journal of molecular sciences · 2022Review
- Article
- Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events.Journal of theoretical biology · 2021Article
- Mitochondrial Genome Evolution of Placozoans: Gene Rearrangements and Repeat Expansions.Genome biology and evolution · 2021Article
- Repeats in mitochondrial and chloroplast genomes characterize the ecotypes of theMolecular breeding : new strategies in plant improvement · 2021Article
- G-Quadruplexes in the Archaea Domain.Biomolecules · 2020Article
- Repetitive DNA profile of the amphibian mitogenome.BMC bioinformatics · 2020Article
- Can Green Algal Plastid Genome Size Be Explained by DNA Repair Mechanisms?Genome biology and evolution · 2020Article
- Structures and stability of simple DNA repeats from bacteria.The Biochemical journal · 2020Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motivation: The NCBI database contains mitochondrial DNA (mtDNA) genomes from numerous species. We investigated the presence and locations of inverted repeat sequences (IRs) in these mtDNA sequences, which are known to be important for regulating nuclear genomes. Results: IRs were identified in mtDNA in all species. IR lengths and frequencies correlate with evolutionary age and the greatest variability was detected in subgroups of plants and fungi and the lowest variability in mammals. IR presence is non-random and evolutionary favoured. The frequency of IRs generally decreased with IR length, but not for IRs 24 or 30 bp long, which are 1.5 times more abundant. IRs are enriched in sequences from the replication origin, followed by D-loop, stem-loop and miscellaneous sequences, pointing to the importance of IRs in regulatory regions of mitochondrial DNA. Availability and implementation: Data were produced using Palindrome analyser, freely available on the web at http://bioinformatics.ibp.cz. Contact: vaclav@ibp.cz. Supplementary information: Supplementary data are available at Bioinformatics online.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.