Evidence map›Paper›PMID 29126099›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2018

Clinical Utility of Select Neuropsychological Assessment Battery Tests in Predicting Functional Abilities in Dementia.

Lee Ashendorf, Michael L Alosco, Hanaan Bing-Canar, Kimberly R Chapman, Brett Martin, Christine E Chaisson, Diane Dixon, Eric G Steinberg, Yorghos Tripodis, Neil W Kowall and 1 more

Abstract read
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. The Neuropsychological Assessment Battery Driving Scenes Test in a Dementia Clinic.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lee AshendorfDepartment of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.
Michael L AloscoBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Hanaan Bing-CanarBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Kimberly R ChapmanBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Brett MartinBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Christine E ChaissonBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Diane DixonBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Eric G SteinbergBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Yorghos TripodisBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Neil W KowallBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Robert A SternBoston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts, USA.

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Neuropathology CoreP30AG013846 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOWALL, NEIL W. · 1996 to 2020
$29.1M
Magnetic Resonance Spectroscopy as a Biomarker for Chronic Traumatic EncephalopathyF32NS096803 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ALOSCO, MICHAEL · 2016 to 2017
$118k
NCATS NIH HHS UL1 TR001430NIA NIH HHS P30 AG013846NINDS NIH HHS F32 NS096803
6 · The paper itself

Abstract

objectiveNeuropsychological test performance can provide insight into functional abilities in patients with dementia, particularly in the absence of an informant. The relationship between neuropsychological measures and instrumental activities of daily living (IADLs) is unclear due to hetereogeneity in cognitive domains assessed and neuropsychological tests administered. Practical and ecologically valid performance-based measures of IADLs are also limited. The Neuropsychological Assessment Battery (NAB) is uniquely positioned to provide a dual-purpose assessment of cognitive and IADL function, as it includes Daily Living tests that simulate real-world functional tasks. We examined the utility of select NAB tests in predicting informant-reported IADLs in mild cognitive impairment and dementia.

methodsThe sample of 327 participants included 128 normal controls, 97 individuals with mild cognitive impairment, and 102 individuals with Alzheimer's disease dementia from the Boston University Alzheimer's Disease Center research registry. Informants completed the Lawton Brody Instrumental Activities of Daily Living Scale, and study participants were administered selected NAB tests that were complementary to the existing protocol.

resultsROC curves showed strongest prediction of IADL (AUC > 0.90) for memory measures (List Learning delayed recall and Daily Living Memory delayed recall) and Daily Living Driving Scenes. At a predetermined level of specificity (95%), List Learning delayed recall (71%) and Daily Living Memory delayed recall (88%) were the most sensitive. The Daily Living Memory and Driving Scenes tests strongly predicted IADL status, and the other Daily Living tests contributed unique variance.

conclusionsNAB memory measures and Daily Living Tests may have clinical utility in detecting informant-rated functional impairment in dementia.

Indexed as

Neuropsychological TestsActivities of Daily LivingAgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionDementiaExecutive FunctionFemaleHumansLearningMaleMental Recall

Identifiers

PMID29126099
PMCPMC6116785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.