Evidence map›Paper›PMID 29125899›Full record

ArticleArthritis care & research2018

Demographic and Clinical Factors Associated With Nonsurgical Osteoarthritis Treatment Among Patients in Outpatient Clinics.

Lauren M Abbate, Amy S Jeffreys, Cynthia J Coffman, Todd A Schwartz, Liubov Arbeeva, Leigh F Callahan, Nicole A Negbenebor, Wendy M Kohrt, Robert S Schwartz, Ernest Vina and 1 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Arthritis care & research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Lauren M AbbateVeterans Affairs Eastern Colorado Healthcare System, Denver, and University of Colorado School of Medicine, Aurora.
Amy S JeffreysVeterans Affairs Medical Center, Durham, North Carolina.
Cynthia J CoffmanVeterans Affairs Medical Center and Duke University Medical Center, Durham, North Carolina.
Todd A SchwartzGillings School of Global Public Health, University of North Carolina, Chapel Hill.
Liubov ArbeevaUniversity of North Carolina, Chapel Hill.
Leigh F CallahanUniversity of North Carolina, Chapel Hill.
Nicole A NegbeneborWarren Alpert Medical School at Brown University, Providence, Rhode Island.
Wendy M KohrtVeterans Affairs Eastern Colorado Healthcare System, Denver, and University of Colorado School of Medicine, Aurora.
Robert S SchwartzVeterans Affairs Eastern Colorado Healthcare System, Denver, and University of Colorado School of Medicine, Aurora.
Ernest VinaUniversity of Arizona College of Medicine, Tucson.
Kelli D AllenVeterans Affairs Medical Center, Durham, and University of North Carolina, Chapel Hill.
University of North Carolina at Chapel Hill · USVA Eastern Colorado Health Care System · USDurham VA Medical Center · USBrown University · USDuke University Hospital · USUniversity of Arizona · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
NIAMS Multidisciplinary Clinical Research CenterP60AR064166 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 2013 to 2017
$5.8M
Biomarkers to Advance Clinical Phenotypes of Low Back Pain (BACk)R01AR071440 · NIAMS · DUKE UNIVERSITY · PI Adam Goode · 2017 to 2026
$5.0M
Johnston County Osteoarthritis Project: Arthritis, Disability, and Other Chronic DiseasesU01DP006266 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2016 to 2020
$3.8M
Patient and Provider Interventions for Managing Osteoarthritis in Primary CareR01AR059673 · NIAMS · DUKE UNIVERSITY · PI ALLEN, KELLI D., ODDONE, EUGENE Z. · 2010 to 2014
$3.2M
Joint Hypermobility and Lower Body OsteoarthritisR01AR067743 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLIGHTLY, YVONNE M · 2015 to 2018
$1.6M
Quality and Equity in Osteoarthritis: Understanding & Improving Treatment UseK23AR067226 · NIAMS · UNIVERSITY OF ARIZONA · PI VINA, ERNEST R · 2015 to 2019
$834k
Patient and Provider Interventions for Managing Osteoarthritis in Primary CareI01HX000449 · VA · DURHAM VA MEDICAL CENTER · PI ALLEN, KELLI D. · 2011 to 2011
–
HSRD VA I01 HX000449NCCDPHP CDC HHS U01 DP006266NIAMS NIH HHS K23 AR067226NIAMS NIH HHS P60 AR049465NIAMS NIH HHS P60 AR064166NIAMS NIH HHS R01 AR059673NIAMS NIH HHS R01 AR071440NIA NIH HHS P30 AG028716NIDDK NIH HHS P30 DK048520Patient-Centered Outcomes Research Institute CER-1306-02043
6 · The paper itself

Abstract

objectiveTo identify patient demographic and clinical characteristics associated with osteoarthritis (OA) treatment use.

methodsThis was a secondary data analysis of 3 clinical trials among patients with hip or knee OA conducted in Duke Primary Care practices, the Durham Veterans Affairs (VA) Health Care System, and the University of North Carolina-Chapel Hill (UNC). At baseline, participants reported sociodemographic characteristics, OA-related pain and function, and OA treatment use, including oral analgesics, topical creams, joint injections, and physical therapy. Separate, multivariable logistic models (adjusted for clustering of clinics and providers for the Duke and VA cohorts) were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) for the associations between participant characteristics and each type of OA treatment.

resultsOral analgesic use was reported by 70-82% of participants across the 3 cohorts. Physical therapy, knee injections, and topical creams were used by 39-52%, 55-60%, and 25-39% of Duke, VA, and UNC participants, respectively. In multivariable models, worse pain, stiffness, and function, per 5-unit increase, were associated with greater odds of using any oral analgesic for the cohorts from Duke (OR 1.18 [95% CI 1.08-1.28]) and UNC (OR 1.14 [95% CI 1.05-1.24]), but not for the VA cohort (OR 1.04 [95% CI 0.95-1.14]). For all 3 cohorts, nonwhites had higher odds of using topical creams compared to whites.

conclusionResults suggest potential underutilization of therapies other than oral analgesics. Patient characteristics may affect OA treatment use, and understanding the relationship between these factors and OA treatment preferences may improve adherence to OA treatment guidelines.

Indexed as

Pain MeasurementAdministration, OralAdministration, TopicalAgedAmbulatory CareAmbulatory Care FacilitiesAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalConservative TreatmentFemaleFollow-Up StudiesHumansInjections, Intra-ArticularLogistic ModelsMaleMiddle AgedAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID29125899
PMCPMC5945338
OpenAlexW2767554845

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.