ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019
Matched increases in cerebral artery shear stress, irrespective of stimulus, induce similar changes in extra-cranial arterial diameter in humans.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- The Impact of Cocoa Flavanols in Modulating Resting Cerebral Blood Flow During Prolonged Sitting in Healthy Young and Older Adults.Nutrients · 2025Trial
- The independent and combined effects of aerobic exercise intensity and dose differentially increase post-exercise cerebral shear stress and blood flow.Experimental physiology · 2024Trial
- Intracranial vasomotor and blood flow responses to light-intensity aerobic exercise in young adults: a 4D flow MRI study.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Cerebrovascular flow-mediated dilation in humans: Methodological challenges, physiological interpretation and future integrations.Experimental physiology · 2026Review
- Optimizing cerebrovascular endothelial health through shear stress modulation.Experimental physiology · 2025Review
- Age alters integrated cerebrovascular and cardiovascular dynamic responses to exercise: insights from a systems modeling approach.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- No difference in mean middle cerebral artery blood velocity responses between lower- and upper-body unilateral resistance exercise in untrained individuals.Experimental physiology · 2025Article
- A computational framework for quantifying blood flow dynamics across myogenically-active cerebral arterial networks.Biomechanics and modeling in mechanobiology · 2025Article
- Oxidative stress suppresses internal carotid artery dilation to hypercapnia in healthy older adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Handgrip exercise does not alter COExperimental physiology · 2023Article
- Article
- Dynamic resistance exercise-induced pressor response does not alter hypercapnia-induced cerebral vasodilation in young adults.European journal of applied physiology · 2023Article
- Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis.Journal of clinical monitoring and computing · 2022Article
- Dynamic onset response of the internal carotid artery to hypercapnia is blunted in children compared with adults.Physiological reports · 2022Article
- High-but not moderate-intensity exercise acutely attenuates hypercapnia-induced vasodilation of the internal carotid artery in young men.European journal of applied physiology · 2021Article
- Greater increase in internal carotid artery shear rate during aerobic interval compared to continuous exercise in healthy adult men.Physiological reports · 2021Article
- Shearing the brain.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Habitual cigarette smoking attenuates shear-mediated dilation in the brachial artery but not in the carotid artery in young adults.Physiological reports · 2020Article
- Cerebral blood flow responses to exercise are enhanced in left ventricular assist device patients after an exercise rehabilitation program.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Cerebrovascular Function in the Large Arteries Is Maintained Following Moderate Intensity Exercise.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanistic role of arterial shear stress in the regulation of cerebrovascular responses to physiological stimuli (exercise and hypercapnia) is poorly understood. We hypothesised that, if shear stress is a key regulator of arterial dilation, then matched increases in shear, induced by distinct physiological stimuli, would trigger similar dilation of the large extra-cranial arteries. Participants ( n = 10) participated in three 30-min experimental interventions, each separated by ≥48 h: (1) mild-hypercapnia (F
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