ArticleTherapeutic delivery2017
Pulmonary aerosol delivery and the importance of growth dynamics.
Article in Therapeutic delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- From Aerosol to Signal: Advances in Biosensor Technologies for Airborne Biothreat Detection.Biosensors · 2025Review
- Aerosol Fluorescent Labeling via Probe Molecule Volatilization.Analytical chemistry · 2024Article
- Towards More Precise Targeting of Inhaled Aerosols to Different Areas of the Respiratory System.Pharmaceutics · 2024Review
- Aerosol pulmonary immune engineering.Advanced drug delivery reviews · 2023Review
- Pulmonary drug delivery for acute respiratory distress syndrome.Pulmonary pharmacology & therapeutics · 2023Review
- Engineering of inhalable nano-in-microparticles for co-delivery of small molecules and miRNAs.Discover nano · 2023Article
- How to engineer aerosol particle properties and biopharmaceutical performance of propellant inhalers.International journal of pharmaceutics · 2023Article
- Menthol flavoring in e-cigarette condensate causes pulmonary dysfunction and cytotoxicity in precision cut lung slices.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Heat Wave and Bushfire Meteorology in New South Wales, Australia: Air Quality and Health Impacts.International journal of environmental research and public health · 2022Article
- A database for deliquescence and efflorescence relative humidities of compounds with atmospheric relevance.Fundamental research · 2022Review
- Airborne transmission of respiratory viruses.Science (New York, N.Y.) · 2021Review
- Inhaled aerosols: Their role in COVID-19 transmission, including biophysical interactions in the lungs.Current opinion in colloid & interface science · 2021Review
- Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung.International journal of environmental research and public health · 2021Article
- Transport and deposition of hygroscopic particles in asthmatic subjects with and without airway narrowing.Journal of aerosol science · 2020Article
- In-vitro and in-vivo respiratory deposition of a developed metered dose inhaler formulation of an anti-migraine drug.Drug delivery · 2019Article
- MultiscaleCurrent opinion in biomedical engineering · 2019Article
- Biological Obstacles for IdentifyingPharmaceutics · 2019Review
- Negatively-charged aerosol improves burn wound healing by promoting eNOS-dependent angiogenesis.American journal of translational research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aerosols are dynamic systems, responding to variations in the surrounding environmental conditions by changing in size, composition and phase. Although, widely used in inhalation therapies, details of the processes occurring on aerosol generation and during inhalation have received little attention. Instead, research has focused on improvements to the formulation of the drug prior to aerosolization and the resulting clinical efficacy of the treatment. Here, we highlight the processes that occur during aerosol generation and inhalation, affecting aerosol disposition when deposited and, potentially, impacting total and regional doses. In particular, we examine the response of aerosol particles to the humid environment of the respiratory tract, considering both the capacity of particles to grow by absorbing moisture and the timescale for condensation to occur. [Formula: see text].
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.