ArticleInfection2018
Improvement of semen parameters after antibiotic therapy in asymptomatic infertile men infected with Mycoplasma genitalium.
Article in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Genital mycoplasma infection: a systematic review and meta-analysis.Reproductive health · 2023Pooled it
- Evaluation of the Presence of Bacterial and Viral Agents in the Semen of Infertile Men: A Systematic and Meta-Analysis Review Study.Frontiers in medicine · 2022Pooled it
- Clinical Manifestations and Associated Disease States withOpen forum infectious diseases · 2026Article
- Epidemiology, Etiopathogenesis, Diagnosis, and Treatment of Male Infertility-Current Trends and Future Directions: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Semen Microbiome, Male Infertility, and Reproductive Health.International journal of molecular sciences · 2025Review
- The possible pathogenic mechanisms of microorganisms in infertility: a narrative review.Archives of microbiology · 2025Review
- Prevalence ofEthiopian journal of health sciences · 2023Article
- Ureaplasma urealyticum induces polymorphonuclear elastase to change semen properties and reduce sperm motility: a prospective observational study.The Journal of international medical research · 2022Observational
- Semen dysbiosis-just a male problem?Frontiers in cellular and infection microbiology · 2022Review
- Effect of bacterial infection on sperm quality and DNA fragmentation in subfertile men with Leukocytospermia.BMC molecular and cell biology · 2021Article
- Microbiome Compositions From Infertile Couples SeekingFrontiers in cellular and infection microbiology · 2021Article
- Potential Pathogenic Bacteria in Seminal Microbiota of Patients with Different Types of Dysspermatism.Scientific reports · 2020Article
- Leukocytospermia is not an informative predictor of positive semen culture in infertile men: results from a validation study of available guidelines.Human reproduction open · 2020Article
- Study of seminal infection among an infertile male population in Qom, Iran, and its effect on sperm quality.Iranian journal of microbiology · 2018Article
- The influence ofAsian journal of andrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo elucidate the association between asymptomatic infections caused by Mycoplasma genitalium and male infertility, and evaluate the role of antibiotic therapy in treatment of this failure.
methodsA total of 165 infertile males having abnormal semen parameters (study group) and 165 healthy fertile men (control group) were included. Semen samples were taken from all participants and after analyzing for semen parameters, undergone real-time PCR, microbial culture, and reactive oxygen species (ROS), as well as total antioxidant capacity (TAC) assays. Infected individuals of study group were treated with antibiotic. One month after the treatment completion, second semen samples were taken and subjected to all the tests mentioned. The data were analyzed using SPSS statistical software, version 22.0.
resultsThe frequency of M. genitalium was significantly higher in the infertile men compared with the fertile ones (9.7% vs. 1.2%; p = 0.001). Mean cycle threshold (C
conclusionsAsymptomatic infection caused by M. genitalium is correlated with male infertility and antibiotic therapy can improve the semen quality and be used to treat male infertility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.