Evidence map›Paper›PMID 29124630›Full record

Trial reportSleep & breathing = Schlaf & Atmung2018

Effectiveness of inspiratory muscle training on sleep and functional capacity to exercise in obstructive sleep apnea: a randomized controlled trial.

Adília Karoline Ferreira Souza, Armèle Dornelas de Andrade, Ana Irene Carlos de Medeiros, Maria Inês Remígio de Aguiar, Taciano Dias de Souza Rocha, Rodrigo Pinto Pedrosa, Anna Myrna Jaguaribe de Lima

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07329049 (The Effect of Inspiratory Muscle Training on Cognitive Functions, Cerebral Oxygenation, and Neurotrophic Factor Level in Patients With Obstructive Sleep Apnea Syndrome), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 6 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07329049 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Inspiratory Muscle Training on Cognitive Functions, Cerebral Oxygenation, and Neurotrophic Factor Level in Patients With Obstructive Sleep Apnea Syndrome

TypeinterventionalSponsorIstinye UniversityRan2026 to 2027Enrolled42ConditionsObstructive Sleep Apnea Syndrome (OSAS)Armsinspiratory muscle training, Placebo inspiratory muscle training, Usual Care
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  8. Inspiratory muscle training as adjuvant therapy in obstructive sleep apnea: a randomized controlled trial.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Trial
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  11. Exploring Exercise Interventions for Obstructive Sleep Apnea: A Scoping Review.Journal of functional morphology and kinesiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Adília Karoline Ferreira SouzaDepartment of Physical Therapy, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife, PE, 50670-901, Brazil.
Armèle Dornelas de AndradeDepartment of Physical Therapy, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife, PE, 50670-901, Brazil.
Ana Irene Carlos de MedeirosDepartment of Physical Therapy, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife, PE, 50670-901, Brazil.
Maria Inês Remígio de AguiarDepartment of Physical Therapy, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife, PE, 50670-901, Brazil.
Taciano Dias de Souza RochaDepartment of Physical Therapy, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife, PE, 50670-901, Brazil.
Rodrigo Pinto PedrosaSleep and Heart Laboratory, Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, PE, 50100-060, Brazil.
Anna Myrna Jaguaribe de LimaDepartment of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Rua Manoel de Medeiros, s/n - Dois Irmãos, Recife, PE, 52171-900, Brazil. annamyrna@uol.com.br.ORCID http://orcid.org/0000-0002-4224-4009
Universidade Federal de Pernambuco · BRUniversidade de Pernambuco · BRUniversidade Federal Rural de Pernambuco · BR

Funding

Coordination for the Improvement of Higher Education Personnel FACEPE APQ 0234-4.08/13
6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the effectiveness of inspiratory muscle training (IMT) on sleep and functional capacity to exercise in subjects with obstructive sleep apnea (OSA).

methodsThis is a controlled, randomized, double-blind study conducted in 16 OSA patients divided into two groups: training (IMT: n = 8) and placebo-IMT (P-IMT: n = 8). IMT was conducted during 12 weeks with a moderate load (50-60% of maximal inspiratory pressure-MIP), while P-IMT used a load < 20% of MPI. Total daily IMT time for both groups was 30 min, 7 days per week, twice a day.

resultsThere was no difference comparing IMT to P-IMT group after training for lung function (p > 0.05) and respiratory muscle strength (p > 0.05). Maximal oxygen uptake (VO

conclusionAccording to these results, 12 weeks of moderate load IMT resulted in improved sleep quality, but there were no significant repercussions on functional capacity to exercise or excessive daytime sleepiness.

Indexed as

Breathing ExercisesSleepAdultAgedDouble-Blind MethodExerciseFemaleHumansMaleMiddle AgedRespiratory MusclesSleep Apnea, ObstructiveTreatment OutcomeFunctional capacity to exerciseInspiratory muscle trainingObstructive sleep apneaSleep

Identifiers

PMID29124630
OpenAlexW2767786769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.