Evidence map›Paper›PMID 29124418›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation.

Madeline L O'Sullivan, Rebecca A Shelby, Caroline S Dorfman, Sarah A Kelleher, Hannah M Fisher, Krista A Rowe Nichols, Francis J Keefe, Anthony D Sung, Tamara J Somers

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Improved Patient-Reported Outcomes With Post-Transplant Cyclophosphamide: A Quality-of-Life Evaluation and 2-Year Outcomes of BMT CTN 1703.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Madeline L O'SullivanDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA.
Rebecca A ShelbyDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA.
Caroline S DorfmanDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA.
Sarah A KelleherDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA.
Hannah M FisherDepartment of Psychology, University of Miami, 5665 Ponce De Leon Blvd, Coral Gables, FL, USA.
Krista A Rowe NicholsDivision of Hematologic Malignancies and Cellular Therapy, Duke University Medical Center, 2400 Pratt St., Suite 9000, Durham, NC, 27710, USA.
Francis J KeefeDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA.
Anthony D SungDivision of Hematologic Malignancies and Cellular Therapy, Duke University Medical Center, 2400 Pratt St., Suite 9000, Durham, NC, 27710, USA.
Tamara J SomersDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2200 W. Main St., Suite 340, Durham, NC, 27705, USA. tamara.somers@duke.edu.
Duke Medical Center · USDuke University Hospital · USDuke University · USUniversity of Miami · US

Funding

Duke CTSA (Composite)KL2TR001115 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, KRAFT, MONICA · 2013 to 2017
$5.1M
Optimizing Delivery of a Behavioral Cancer Pain Intervention Using a SMARTR01CA202779 · NCI · DUKE UNIVERSITY · PI SOMERS, TAMARA J · 2016 to 2020
$2.8M
Improving Adherence to Recommended Surveillance in Breast Cancer SurvivorsK07CA138767 · NCI · DUKE UNIVERSITY · PI SHELBY, REBECCA A · 2010 to 2014
$788k
Home-Based Tablet Computer Pain Coping Skills Following Stem Cell TransplantR21CA173307 · NCI · DUKE UNIVERSITY · PI SOMERS, TAMARA J · 2013 to 2014
$371k
National Center for Advancing Translational Sciences (US) 5KL2TR001115-03NCATS NIH HHS KL2 TR001115NCI NIH HHS K07 CA138767NCI NIH HHS K07CA138767NCI NIH HHS R01 CA202779NCI NIH HHS R21 CA173307
6 · The paper itself

Abstract

purposePain is common for hematopoietic stem cell transplant (HSCT) patients and may be experienced pre-transplant, acutely post-transplant, and for months or years following transplant. HSCT patients with persistent pain may be at risk for poor quality of life following transplant; however, the impact of pre-transplant pain on quality of life post-transplant is not well understood. Self-efficacy for chronic disease management is associated with quality of life among cancer patients and may impact quality of life for HSCT patients. The primary aim was to examine the effect of pre-transplant pain and self-efficacy on quality of life domains in the year following transplant.

methodsOne hundred sixty-six HSCT patients completed questionnaires providing information on pain, self-efficacy, and quality of life prior to transplant, at discharge, and 3-, 6-, and 12-months post-transplant as part of a longitudinal, observational study. Linear mixed modeling examined the trajectories of these variables and the effect of pre-transplant pain and self-efficacy on post-transplant quality of life.

resultsPain and social and emotional quality of life remained stable in the year following transplant while self-efficacy and physical and functional quality of life improved. Pre-transplant pain was significantly related to lower physical well-being post-transplant. Lower pre-transplant self-efficacy was related to lower quality of life across all domains post-transplant.

conclusionAbove and beyond the effect of pre-transplant pain, self-efficacy for managing chronic disease is important in understanding quality of life following transplant. Identifying patients with pain and/or low self-efficacy pre-transplant may allow for early intervention with self-management strategies.

Indexed as

AdultAgedAged, 80 and overChronic DiseaseEmotionsFemaleHematopoietic Stem Cell TransplantationHumansLinear ModelsLongitudinal StudiesMaleMiddle AgedNeoplasmsPainQuality of LifeSelf EfficacyHSCTPainQuality of lifeSelf-efficacy

Identifiers

PMID29124418
PMCPMC5823743
OpenAlexW2767258057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.