Evidence map›Paper›PMID 29124386›Full record

ArticleEuropean journal of nutrition2019

Olive oil consumption and 10-year (2002-2012) cardiovascular disease incidence: the ATTICA study.

Georgia-Maria Kouli, Demosthenes B Panagiotakos, Ioannis Kyrou, Emanuela Magriplis, Ekavi N Georgousopoulou, Christina Chrysohoou, Constantine Tsigos, Dimitrios Tousoulis, Christos Pitsavos

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In one paragraph

Article in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  17. Metabolic and Vascular Effect of the Mediterranean Diet.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Georgia-Maria KouliDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece.
Demosthenes B PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece. dbpanag@hua.gr.ORCID http://orcid.org/0000-0001-8583-153X
Ioannis KyrouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece.
Emanuela MagriplisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece.
Ekavi N GeorgousopoulouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece.
Christina ChrysohoouFirst Cardiology Clinic, School of Medicine, University of Athens, 115 28, Athens, Greece.
Constantine TsigosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 176 71, Athens, Greece.
Dimitrios TousoulisFirst Cardiology Clinic, School of Medicine, University of Athens, 115 28, Athens, Greece.
Christos PitsavosFirst Cardiology Clinic, School of Medicine, University of Athens, 115 28, Athens, Greece.
Harokopio University of Athens · GRNational and Kapodistrian University of Athens · GRUniversity of Canberra · AUAston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOlive oil, being rich in mono-unsaturated fatty acids and anti-inflammatory compounds, may have protective effects against cardiovascular disease (CVD). The aim of the present work was to examine the association of olive oil consumption with the 10-year CVD incidence in adults without pre-existing CVD.

methodsThe ATTICA Study is a prospective, population-based study conducted in the greater metropolitan area of Athens (Attica, Greece). During 2001-2002, 3042 CVD-free adults (1514 men and 1528 women) were voluntarily recruited to the ATTICA study. Among various dietary habits, consumption of olive oil and other fats/oils was assessed at baseline; participants were classified into three groups (no use; mixed use; and exclusive use of olive oil). In 2011-2012, the 10-year study follow-up was performed, recording the fatal/non-fatal CVD incidence in 2020 participants (mean follow-up duration: 8.41 years).

resultsAfter controlling for various covariates, an inverse association between exclusive olive oil use and the risk of developing CVD was observed (relative risk 0.07, 95% CI: 0.01-0.66) compared to those not consuming olive oil. Further adjustment for fibrinogen plasma levels (among various inflammatory markers) showed a significant mediation effect on the previous association.

conclusionsThese findings support exclusive olive oil consumption, a key component of the Mediterranean diet, for the primary CVD prevention, in adults without pre-existing disease. Circulating fibrinogen levels appear to play a mediating role in this relationship.

Indexed as

AdolescentAdultAgedAged, 80 and overCardiovascular DiseasesFeeding BehaviorFemaleGreeceHumansIncidenceMaleMiddle AgedOlive OilProspective StudiesYoung AdultOlive OilCardiovascular diseaseFibrinogenInflammationNutritionOlive oil

Identifiers

PMID29124386
OpenAlexW2767996491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.