ArticleBioprocess and biosystems engineering2018
Rhamnosidase activity of selected probiotics and their ability to hydrolyse flavonoid rhamnoglucosides.
Article in Bioprocess and biosystems engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers.Molecules (Basel, Switzerland) · 2018Trial
- Microbial α-L-Rhamnosidases: Regioselective Biocatalysts for Flavonoid Biotransformation and Nutraceutical Applications.Current issues in molecular biology · 2026Review
- Optimization on production and technological properties of exopolysaccharide from Pediococcus pentosaceus SL4 isolated from sourdough Tomi-tomi (Flacourtia Inermis Roxb).World journal of microbiology & biotechnology · 2026Article
- A Hyperthermostable Archaeal GH78 Rhamnosidase Efficiently Hydrolyzes Flavonoid Glycosides for Juice Debittering.Journal of agricultural and food chemistry · 2026Article
- Metabolic insights of lactic acid bacteria in reducing off-flavors and antinutrients in plant-based fermented dairy alternatives.Comprehensive reviews in food science and food safety · 2025Review
- Advanced Nanotechnological Approaches for Effective Delivery of Rutin: An Updated Review.Pharmaceutical nanotechnology · 2025Review
- Vine Tea Extract Enhanced the Fermentation of Skimmed Milk byFood science & nutrition · 2024Article
- Effects of derivatization and probiotic transformation on the antioxidative activity of fruit polyphenols.Food chemistry: X · 2024Review
- Metabolomic Comparison of Guava (Nutrients · 2024Article
- Pangenome comparison ofbioRxiv : the preprint server for biology · 2023Article
- Combined acid hydrolysis and fermentation improves bioactivity of citrus flavonoids in vitro and in vivo.Communications biology · 2023Article
- Polyphenols as Drivers of a Homeostatic Gut Microecology and Immuno-Metabolic Traits ofInternational journal of molecular sciences · 2022Review
- The Loss-of-Function MutationJournal of fungi (Basel, Switzerland) · 2022Article
- Polyphenol Mechanisms against Gastric Cancer and Their Interactions with Gut Microbiota: A Review.Current oncology (Toronto, Ont.) · 2022Review
- Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea.BMC veterinary research · 2022Article
- Multi-omics reveals the positive leverage of plant secondary metabolites on the gut microbiota in a non-model mammal.Microbiome · 2021Article
- Biotransformation of Flavonoids by Newly Isolated and CharacterizedMicroorganisms · 2021Article
- Polyphenol-Mediated Gut Microbiota Modulation: Toward Prebiotics and Further.Frontiers in nutrition · 2021Review
- Effects of Quercetin and Resveratrol onFrontiers in microbiology · 2019Article
- Microbial metabolism marvels: a comprehensive review of microbial drug transformation capabilities.Gut microbesReview
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Authors and funding
6 authors.
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Abstract
Bioavailability of flavonoids is low, especially when occurring as rhamnoglucosides. Thus, the hydrolysis of rutin, hesperidin, naringin and a mixture of narcissin and rutin (from Cyrtosperma johnstonii) by 14 selected probiotics was tested. All strains showed rhamnosidase activity as shown using 4-nitrophenyl α-L-rhamnopyranoside as a substrate. Hesperidin was hydrolysed by 8-27% after 4 and up to 80% after 10 days and narcissin to 14-56% after 4 and 25-97% after 10 days. Rutin was hardly hydrolysed with a conversion rate ranging from 0 to 5% after 10 days. In the presence of narcissin, the hydrolysis of rutin was increased indicating that narcissin acts as an inducer. The rhamnosidase activity as well as the ability to hydrolyse flavonoid rhamnoglucosides was highly strain specific. Naringin was not hydrolysed by rhamnosidase from probiotics, not even by the purified recombinant enzyme, only by fungal rhamnosidase. In conclusion, rhamnosidases from the tested probiotics are substrate specific cleaving hesperidin, narcissin and to a small extent rutin, but not naringin.
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