ReviewEuropean journal of applied physiology2018
Changes in fat oxidation in response to various regimes of high intensity interval training (HIIT).
Review in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis of randomized controlled studies.Frontiers in endocrinology · 2025Pooled it
- High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover.Physiological reports · 2021Trial
- The day-to-day reliability of peak fat oxidation and FATEuropean journal of applied physiology · 2020Trial
- Metabolic and Cardiorespiratory Differences in Incremental Upper and Lower-Body Exercise in Healthy Adults-A Cross-Over Trial.Sports (Basel, Switzerland) · 2026Article
- The effect of aerobic exercise with blood flow restriction on substrate utilization and energy expenditure.Frontiers in sports and active living · 2026Article
- A Novel Two-Week Dynamic HIIT Protocol Improves Roller Skiing Speed and Metabolic Efficiency in Trained Cross-Country Skiers: A Pilot Study.Journal of functional morphology and kinesiology · 2025Article
- Exercise training restores longevity-associated tryptophan metabolite 3-hydroxyanthranilic acid levels in middle-aged adults.Acta physiologica (Oxford, England) · 2025Article
- Effects of 10 weeks of walking-based exercise training on resting substrate oxidation in postmenopausal women with obesity.European journal of clinical nutrition · 2025Article
- Exercise Testing for Metabolic Flexibility: Time for Protocol Standardization.Sports medicine - open · 2025Article
- Article
- Customizing intense interval exercise training prescription using the "frequency, intensity, time, and type of exercise" (FITT) principle.Frontiers in physiology · 2025Review
- Effects of recreational team sports on the metabolic health, body composition and physical fitness parameters of overweight and obese populations: A systematic review.Biology of sport · 2024Review
- The role of GPR81-cAMP-PKA pathway in endurance training-induced intramuscular triglyceride accumulation and mitochondrial content changes in rats.The journal of physiological sciences : JPS · 2024Article
- A Synthetic ERR Agonist Alleviates Metabolic Syndrome.The Journal of pharmacology and experimental therapeutics · 2024Article
- Chronic high-intensity interval training and moderate-intensity continuous training are both effective in increasing maximum fat oxidation during exercise in overweight and obese adults: A meta-analysis.Journal of exercise science and fitness · 2023Review
- Applied high-intensity interval cardio yoga improves cardiometabolic fitness, energetic contributions, and metabolic flexibility in healthy adults.Frontiers in physiology · 2023Article
- Treatment with EV-miRNAs Alleviates Obesity-Associated Metabolic Dysfunction in Mice.International journal of molecular sciences · 2022Article
- Isolated and combined impact of dietary olive oil and exercise on markers of health and energy metabolism in female mice.The Journal of nutritional biochemistry · 2022Article
- High Intensity Interval Training: A Potential Method for Treating Sarcopenia.Clinical interventions in aging · 2022Review
- Effects of Exercise in Improving Cardiometabolic Risk Factors in Overweight Children: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased whole-body fat oxidation (FOx) has been consistently demonstrated in response to moderate intensity continuous exercise training. Completion of high intensity interval training (HIIT) and its more intense form, sprint interval training (SIT), has also been reported to increase FOx in different populations. An explanation for this increase in FOx is primarily peripheral adaptations via improvements in mitochondrial content and function. However, studies examining changes in FOx are less common in response to HIIT or SIT than those determining increases in maximal oxygen uptake which is concerning, considering that FOx has been identified as a predictor of weight gain and glycemic control. In this review, we explored physiological and methodological issues underpinning existing literature concerning changes in FOx in response to HIIT and SIT. Our results show that completion of interval training increases FOx in approximately 50% of studies, with the frequency of increased FOx higher in response to studies using HIIT compared to SIT. Significant increases in β-HAD, citrate synthase, fatty acid binding protein, or FAT/CD36 are likely responsible for the greater FOx seen in these studies. We encourage scientists to adopt strict methodological procedures to attenuate day-to-day variability in FOx, which is dramatic, and develop standardized procedures for assessing FOx, which may improve detection of changes in FOx in response to HIIT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.