Evidence map›Paper›PMID 29124320›Full record

ReviewSeminars in immunopathology2018

Recipe for IBD: can we use food to control inflammatory bowel disease?

Mario Witkowski, Marco Witkowski, Nicola Gagliani, Samuel Huber

Open access · hybridAbstract readReview
In one paragraph

Review in Seminars in immunopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Relieving Effect ofAntioxidants (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Nutrients · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Development of Anti-inflammatory ProbioticFrontiers in microbiology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mario WitkowskiInstitute of Medical Microbiology and Hygiene, University of Mainz Medical Centre, Mainz, Germany.
Marco WitkowskiDepartment of Internal Medicine and Cardiology, Campus Benjamin Franklin, Charité - Universitätsmedizin, Berlin, Germany.
Nicola GaglianiDepartment of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Samuel HuberDepartment of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. shuber@uke.de.ORCID 0000-0001-9325-8227
Johannes Gutenberg University Mainz · DEUniversität Hamburg · DE

Funding

FP7 Ideas: European Research Council 337251FP7 Ideas: European Research Council 715271
6 · The paper itself

Abstract

The mucosal immune system and the microbiota in the intestinal tract have recently been shown to play a key role in the pathogenesis of inflammatory bowel disease (IBD). Both of these can be influenced by food. Thus, we propose dietary intervention as a therapeutic option for IBD. In this review, we discuss the interaction of the intestinal mucosal immune system and the intestinal microbiota in the context of IBD. In addition, we discuss the impact of food components on immune responses in IBD. Finally, we address the current evidence of how this interaction (i.e., immune system-microbiota) can be modulated by food components, pre/probiotics, and fecal microbiota transplantation (FMT) and how these approaches can support intestinal homeostasis. By gathering the vast amount of literature available on the impact of food on IBD, we aim to distinguish between scientifically sound data and theories, which have not been included in this review.

Indexed as

DietAnimalsFecal Microbiota TransplantationGastrointestinal MicrobiomeHumansImmunity, MucosalInflammatory Bowel DiseasesIntestinal MucosaProbiotics

Identifiers

PMID29124320
PMCPMC5809523
OpenAlexW2767420753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.