Evidence map›Paper›PMID 29124214›Full record

ArticleBiochemistry and biophysics reports2015

Gene replacement and quantitative mass spectrometry approaches validate guanosine monophosphate synthetase as essential for

Anne Drumond Villela, Paula Eichler, Antonio Frederico Michel Pinto, Valnês Rodrigues-Junior, John R Yates Iii, Cristiano Valim Bizarro, Luiz Augusto Basso, Diógenes Santiago Santos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anne Drumond VillelaInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Paula EichlerInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Antonio Frederico Michel PintoInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Valnês Rodrigues-JuniorInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
John R Yates IiiDepartment of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA.
Cristiano Valim BizarroInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Luiz Augusto BassoInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Diógenes Santiago SantosInstituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Avenida Ipiranga, 6681, TecnoPUC 92A, 90619-900 Porto Alegre, RS, Brazil.
Pontifícia Universidade Católica do Rio Grande do Sul · BRHospital São Lucas da PUCRS · BRScripps Research Institute · US

Funding

ZDS2P REGULATES SWE1P-DEPENDENT POLARIZED CELL GROWTH IN S CEREVISIAEP41RR011823 · NCRR · UNIVERSITY OF WASHINGTON · PI SALVESEN, GUY S. · 1996 to 2011
$24.7M
TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
NCRR NIH HHS P41 RR011823NIGMS NIH HHS P41 GM103533
6 · The paper itself

Abstract

Guanosine monophosphate synthetase (GMPS), encoded by

Indexed as

Essential geneGuaA geneGuanosine monophosphate synthetaseMass spectrometryMycobacterium tuberculosisNucleotide biosynthesis

Identifiers

PMID29124214
PMCPMC5669397
OpenAlexW2194856489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.