ArticleBiochemistry and biophysics reports2015
The double mutation of cytochrome P450's and fatty acid desaturases affect lipid regulation and longevity in
Article in Biochemistry and biophysics reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- A gut-activated NHR-86-CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis.PLoS biology · 2026Article
- Transcriptome Analysis Reveals Norathyriol Prolongs the Lifespan via Regulating Metabolism inMetabolites · 2024Article
- Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model.GeroScience · 2024Article
- Titanium Dioxide (TiOToxics · 2023Article
- Combinatorial interventions in aging.Nature aging · 2023Review
- Protective Effect ofNutrients · 2023Article
- Complementary biological and computational approaches identify distinct mechanisms of chlorpyrifos versus chlorpyrifos-oxon-induced dopaminergic neurotoxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Correlated evolution of social organization and lifespan in mammals.Nature communications · 2023Article
- CYP35 family in Caenorhabditis elegans biological processes: fatty acid synthesis, xenobiotic metabolism, and stress responses.Archives of toxicology · 2022Review
- Astaxanthin Induces Transcriptomic Responses Associated with Lifespan Extension inAntioxidants (Basel, Switzerland) · 2022Article
- Cytochromes P450 ofBiomolecules · 2022Review
- Benzo[a]pyrene and Caenorhabditis elegans: defining the genotoxic potential in an organism lacking the classical CYP1A1 pathway.Archives of toxicology · 2021Article
- Phenolic Compounds Reduce the Fat Content inPharmaceuticals (Basel, Switzerland) · 2020Article
- Cytochrome P450 metabolism mediates low-temperature resistance in pinewood nematode.FEBS open bio · 2020Article
- The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegans.Environmental toxicology and pharmacology · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An imbalance between energy uptake and energy expenditure can lead to obesity and increase the risk of coronary heart disease, high blood pressure, stroke, type II diabetes and some cancers. Given that key elements of the energy pathway are evolutionary conserved, invertebrate research is an attractive alternative that overcomes the many legislative, financial and experimental hurdles typical of research with higher metazoan animals. Recent studies have suggested that some members of the cytochrome P450 superfamily are involved in lipid metabolism in addition to the traditional xenobiotic activity. To investigate this notion in more detail, the present study aimed to pinpoint phenotypic, genetic and genomic-level responses of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.