Evidence map›Paper›PMID 29124110›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2017

Characterization of

Akira Nishimura, Hidenori Nonomura, Shingo Tanaka, Michihiro Yoshida, Yuka Maruyama, Yutaka Aritomi, Ann M Saunders, Daniel K Burns, Michael W Lutz, Grant Runyan and 3 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Use of local genetic ancestry to assessNeurology. Genetics · 2020
    Article
  5. Frontiers in aging neuroscience · 2020
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Akira NishimuraTakeda Pharmaceutical Company Limited, Osaka, Japan.
Hidenori NonomuraTakeda Pharmaceutical Company Limited, Osaka, Japan.
Shingo TanakaTakeda Pharmaceutical Company Limited, Osaka, Japan.
Michihiro YoshidaTakeda Pharmaceutical Company Limited, Osaka, Japan.
Yuka MaruyamaZinfandel Pharmaceuticals, Inc., Chapel Hill, NC, USA.
Yutaka AritomiTakeda Pharmaceutical Company Limited, Osaka, Japan.
Ann M SaundersZinfandel Pharmaceuticals, Inc., Chapel Hill, NC, USA.
Daniel K BurnsZinfandel Pharmaceuticals, Inc., Chapel Hill, NC, USA.
Michael W LutzDuke University School of Medicine, Durham, NC, USA.
Grant RunyanTakeda Development Center Americas, Inc., Deerfield, IL, USA.
Eric LaiTakeda Development Center Americas, Inc., Deerfield, IL, USA.
Kumar BudurTakeda Development Center Americas, Inc., Deerfield, IL, USA.
Allen D RosesZinfandel Pharmaceuticals, Inc., Chapel Hill, NC, USA.
Takeda (Japan) · JPDeerfield (United States) · USDuke University · USTakeda (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDementia is one of the major health threats to our aging society, and Alzheimer's disease (AD) is the leading cause. In Japan, ∼15% of the elderly population has dementia. The apolipoprotein E (

methodsWhole blood samples were collected from 300 Japanese subjects, and genomic DNA was extracted to determine

resultsOur results indicated that the DISCUSSION: A biomarker risk assignment algorithm, using a combination of

Indexed as

Allele frequencyAlzheimer's diseaseApolipoprotein E (APOE)JapanesePoly-thymine (poly-T) variantsTranslocase of outer mitochondrial membrane 40 (TOMM40)

Identifiers

PMID29124110
PMCPMC5671626
OpenAlexW2750686292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.