Evidence map›Paper›PMID 29124067›Full record

ArticleBioMed research international2017

Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study.

Tove Wallstrom, Hans Jarnbert-Pettersson, David Stenson, Helena Akerud, Elisabeth Darj, Kristina Gemzell-Danielsson, Eva Wiberg-Itzel

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tove WallstromDepartment of Clinical Science and Education, Karolinska Institutet, Women's Clinic, Sodersjukhuset, Sweden.
Hans Jarnbert-PetterssonDepartment of Clinical Science and Education, Karolinska Institutet, Women's Clinic, Sodersjukhuset, Sweden.
David StensonDepartment of Clinical Science and Education, Karolinska Institutet, Women's Clinic, Sodersjukhuset, Sweden.
Helena AkerudDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Elisabeth DarjDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Kristina Gemzell-DanielssonDepartment of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Eva Wiberg-ItzelDepartment of Clinical Science and Education, Karolinska Institutet, Women's Clinic, Sodersjukhuset, Sweden.ORCID 0000-0002-4835-9616
Karolinska Institutet · SEUppsala University · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOne great challenge in obstetric care is labor inductions. Misoprostol has advantages in being cheap and stable at room temperature and available in resource-poor settings. MATERIAL AND

methodsRetrospective cohort study of 4002 singleton pregnancies with a gestational age ≥34 w at Sodersjukhuset, Stockholm, during 2009-2010 and 2012-2013. Previously used methods of labor induction were compared with misoprostol given as a solution to drink, every second hour. Main outcome is as follows: Cesarean Section (CS) rate, acid-base status in cord blood, Apgar score < 7,5', active time of labor, and blood loss > 1500 ml (PPH).

resultsThe proportion of CS decreased from 26% to 17% when orally given solution of misoprostol was introduced at the clinic (

conclusionInduction of labor with misoprostol, given as an oral solution to drink every second hour, gives a low rate of CS, without affecting maternal or fetal outcome.

Indexed as

Labor, InducedAdministration, OralAdultCesarean SectionFemaleHumansMisoprostolOdds RatioPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsMisoprostol

Identifiers

PMID29124067
PMCPMC5624161
OpenAlexW2754897331

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.