Evidence map›Paper›PMID 29123848›Full record

ArticleAcute medicine & surgery2017

A case of type 2 diabetes mellitus with metformin-associated lactic acidosis initially presenting the appearance of a sulfonylurea-related hypoglycemic attack.

Kota Nishihama, Kanako Maki, Yuko Okano, Rei Hashimoto, Yasuhiro Hotta, Mei Uemura, Taro Yasuma, Toshinari Suzuki, Toyomi Hayashi, Eiji Ishikawa and 4 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Acute medicine & surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kota NishihamaDepartment of Diabetes, Metabolism and Endocrinology Mie University Graduate School of Medicine Tsu Japan.
Kanako MakiDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Yuko OkanoDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Rei HashimotoDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Yasuhiro HottaDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Mei UemuraDepartment of Diabetes, Metabolism and Endocrinology Mie University Graduate School of Medicine Tsu Japan.
Taro YasumaDepartment of Immunology Mie University Graduate School of Medicine Tsu Japan.
Toshinari SuzukiDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Toyomi HayashiDepartment of Diabetes and Endocrinology Mie University Hospital Tsu Japan.
Eiji IshikawaDepartment of Cardiology and Nephrology Mie University Graduate School of Medicine Tsu Japan.
Yutaka YanoDepartment of Diabetes, Metabolism and Endocrinology Mie University Graduate School of Medicine Tsu Japan.
Esteban C GabazzaDepartment of Immunology Mie University Graduate School of Medicine Tsu Japan.
Masaaki ItoDepartment of Cardiology and Nephrology Mie University Graduate School of Medicine Tsu Japan.
Yoshiyuki TakeiDepartment of Gastroenterology and Hepatology Mie University Graduate School of Medicine Tsu Japan.
Mie University · JPMie University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Case: A 64-year-old Japanese woman with diabetes mellitus was admitted for hypoglycemia. Her diabetes had been under good control with glimepiride, voglibose, exenatide, and metformin for a few years. Although overt proteinuria was observed, the serum creatinine values were within normal range during the routine outpatient follow-up. Hypoglycemic attack caused by glimepiride and loss of appetite by urinary tract infection were diagnosed. Then, metformin-associated lactic acidosis with acute renal failure caused by dehydration was detected. Outcome: Her condition was improved by continuous veno-venous hemodiafiltration and hemodialysis, known to be useful to remove metformin. Conclusion: We reported a case of metformin-associated lactic acidosis with hypoglycemia during routine treatment of diabetes that was successfully rescued by early renal replacement therapy.

Indexed as

Diabetes mellitushemodialysishypoglycemialactic acidosismetformin

Identifiers

PMID29123848
PMCPMC5667282
OpenAlexW2500092860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.