Evidence map›Paper›PMID 29123765›Full record

ArticleAcute medicine & surgery2016

Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage.

Masahiro Kashiura, Hiroshi Fujita, Kazuhiro Sugiyama, Akiko Akashi, Yuichi Hamabe

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Acute medicine & surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Masahiro KashiuraTertiary Emergency Medical Center Tokyo Metropolitan Bokutoh Hospital Tokyo Japan.
Hiroshi FujitaDepartment of Transfusion Medicine Tokyo Metropolitan Bokutoh Hospital Tokyo Japan.
Kazuhiro SugiyamaTertiary Emergency Medical Center Tokyo Metropolitan Bokutoh Hospital Tokyo Japan.
Akiko AkashiTertiary Emergency Medical Center Tokyo Metropolitan Bokutoh Hospital Tokyo Japan.
Yuichi HamabeTertiary Emergency Medical Center Tokyo Metropolitan Bokutoh Hospital Tokyo Japan.
Tokyo Metropolitan Bokutoh Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Case: An 82-year-old man taking dabigatran was admitted with syncope. Computed tomography showed extravasation from the stomach. Laboratory data revealed renal insufficiency and prolonged activated partial thromboplastin time. The gastric endoscopy showed a gastric ulcer with an exposed vessel. However, an endoscopic hemostatic procedure failed to completely stop the bleeding. The patient experienced cardiac arrest from hypotensive shock. Spontaneous circulation returned after 5 min of resuscitation. After endoscopy, computed tomography showed a gastric perforation. For dabigatran removal, the patient underwent a 6-h hemodialysis session. Thrombin activity and thrombin-antithrombin complex increased during hemodialysis, while activated partial thromboplastin time decreased. Outcome: Good recovery was observed after dialysis and the following gastrectomy. Conclusion: Hemodialysis should be considered for dabigatran removal in cases of life-threatening hemorrhage. The thrombin-antithrombin complex may be useful for monitoring the plasma dabigatran level.

Indexed as

Anticoagulantsdabigatran etexilatehemorrhagepeptic ulcer perforationrenal dialysis

Identifiers

PMID29123765
PMCPMC5667362
OpenAlexW1604846710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.