ArticleIUCrJ2017
The potential of hexatungstotellurate(VI) to induce a significant entropic gain during protein crystallization.
Article in IUCrJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Adaptive Responses of a Peroxidase-like Polyoxometalate-Based Tri-Assembly to Bacterial Microenvironment (BME) Significantly Improved the Anti-Bacterial Effects.International journal of molecular sciences · 2023Article
- Speciation of Transition-Metal-Substituted Keggin-Type Silicotungstates Affected by the Co-crystallization Conditions with Proteinase K.Inorganic chemistry · 2021Article
- Rationalizing the Decavanadate(V) and Oxidovanadium(IV) Binding to G-Actin and the Competition with Decaniobate(V) and ATP.Inorganic chemistry · 2021Article
- Multivalent ions and biomolecules: Attempting a comprehensive perspective.Chemphyschem : a European journal of chemical physics and physical chemistry · 2020Review
- Protein crystal structure determination with the crystallophore, a nucleating and phasing agent.Journal of applied crystallography · 2019Article
- Regioselective synthesis and characterization of monovanadium-substituted β-octamolybdate [VMoActa crystallographica. Section C, Structural chemistry · 2019Article
- Polyoxometalates as Potential Next-Generation Metallodrugs in the Combat Against Cancer.Angewandte Chemie (International ed. in English) · 2019Review
- Iron(II) and copper(II) paratungstates B: a single-crystal X-ray diffraction study.Acta crystallographica. Section C, Structural chemistry · 2018Article
- Synthesis and characterization of hybrid Anderson hexamolybdoaluminates(III) functionalized with indometacin or cinnamic acid.Acta crystallographica. Section C, Structural chemistry · 2018Article
- The P-type ATPase inhibiting potential of polyoxotungstates.Metallomics : integrated biometal science · 2018Article
- The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives.Chemical communications (Cambridge, England) · 2018Article
- Antibacterial Activity of Polyoxometalates AgainstFrontiers in chemistry · 2018Article
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3 authors.
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Abstract
The limiting factor in protein crystallography is still the production of high-quality crystals. In this regard, the authors have recently introduced hexatungstotellurate(VI) (TEW) as a new crystallization additive, which proved to be successful within the liquid-liquid phase separation (LLPS) zone. Presented here are comparative crystal structure analyses revealing that protein-TEW binding not only induces and stabilizes crystal contacts, but also exhibits a significant impact on the solvent-driven crystallization entropy, which is the driving force for the crystallization process. Upon the formation of TEW-mediated protein-protein contacts, the release of water molecules from the hydration shells of both molecules,
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