Evidence map›Paper›PMID 29123579›Full record

ArticlePrzeglad gastroenterologiczny2017

Blood serum levels of E-cadherin in patients with colorectal cancer.

Dariusz Cepowicz, Konrad Zaręba, Anna Pryczynicz, Tomasz Dawidziuk, Joanna Żurawska, Joanna Hołody-Zaręba, Mariusz Gryko, Bogusław Kędra

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Prognostic Significance ofCancer management and research · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dariusz Cepowicz2 Department of General and Gastroenterological Surgery, Medical University of Bialystok, Bialystok, Poland.
Konrad Zaręba2 Department of General and Gastroenterological Surgery, Medical University of Bialystok, Bialystok, Poland.
Anna PryczyniczDepartment of Pathomorphology, Medical University of Bialystok, Bialystok, Poland.
Tomasz Dawidziuk2 Department of General and Gastroenterological Surgery, Medical University of Bialystok, Bialystok, Poland.
Joanna ŻurawskaDepartment of Clinical Molecular Biology, Medical University of Bialystok, Bialystok, Poland.
Joanna Hołody-ZarębaDepartment of Gynaecology and Obstetrics, J. Śniadecki Memorial Voivodeship Hospital, Bialystok, Poland.
Mariusz Gryko2 Department of General and Gastroenterological Surgery, Medical University of Bialystok, Bialystok, Poland.
Bogusław Kędra2 Department of General and Gastroenterological Surgery, Medical University of Bialystok, Bialystok, Poland.
Medical University of Białystok · PLWojewódzki Szpital Zespolony im. Jędrzeja Śniadeckiego · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionColorectal cancer is the second most common cancer in terms of incidence in Poland. It is also the second most common cause of cancer deaths in men and the third women. In 75-80% of cases, depending on sources, it is of an occasional nature, and in the remaining 20-25% it has a hereditary character.

aimTo compare the levels of E-cadherin in blood serum with some histopathological and clinical features. E-cadherin is an adhesion molecule, loss of function of which is suspected to influence both cancer progression and metastasis. MATERIAL AND

methodsThe study group comprised 48 patients diagnosed with colorectal cancer treated surgically in the Second Department of General and Gastroenterological Surgery, Medical University Hospital in Bialystok.

resultsAs has been shown here, there is no statistically significant relationship between the levels of E-cadherin in blood serum and the possible prognosis to the progression of colorectal cancer. However, it was indicated that there appears to be a statistically significant relationship between blood serum E-cadherin levels and the levels of alanine aminotransferase and aspartate aminotransferase in patients with colorectal cancer.

conclusionsThe authors suggest that this significance may require further study.

Indexed as

alanine aminotransferaseaspartate aminotransferasecolon cancercolorectal cancerE-cadherin

Identifiers

PMID29123579
PMCPMC5672706
OpenAlexW2761790393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.