Evidence map›Paper›PMID 29123419›Full record

ArticleInternational journal of general medicine2017

Encephalitis treatment - a case report with long-term follow-up of EBV PCR in cerebrospinal fluid.

Fnu Zarlasht, Mashal Salehi, Mohammad Abu-Hishmeh, Muzammil Khan

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of general medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Fnu ZarlashtDepartment of Medicine, Lourdes Hospital, Binghamton, NY, USA.
Mashal SalehiDepartment of Medicine, NYC Health + Hospital/Harlem, Columbia University, NY, USA.
Mohammad Abu-HishmehDepartment of Medicine, Lincoln Medical and Mental Health Centre, Bronx NY, USA.
Muzammil KhanDepartment of Medicine, NYC Health + Hospital/Harlem, Columbia University, NY, USA.
Columbia University · USHarlem Hospital Center · USLincoln Medical Center · USLourdes Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpstein-Barr virus (EBV) has been found to cause infectious mononucleosis multiple times, but has been associated rarely with EBV encephalitis. Also, whenever it is diagnosed, it is always treated symptomatically. CASE REPORT: A case of confirmed EBV encephalitis is presented, which was treated with antiviral therapy resulting in complete clearance of the virus in cerebrospinal fluid and minimal neurologic symptoms after hospital discharge.

conclusionThe Infectious Diseases Society of America guidelines state that intravenous acyclovir is not recommended for EBV-related encephalitis. But we reviewed the literature and found similar cases, and we believe that antiviral therapy should be recommended for EBV encephalitis because it is a potentially fatal disease and if left untreated, can lead to raised intracranial pressure, craniotomy and even death.

Indexed as

Epstein–Barr virusHIVhuman immune deficiency virusintravenous

Identifiers

PMID29123419
PMCPMC5661833
OpenAlexW2766773473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.