ArticleScientific reports2017
Clinical Parameters and Gut Microbiome Changes Before and After Surgery in Thoracic Aortic Dissection in Patients with Gastrointestinal Complications.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Pharmaco-psychiatry and gut microbiome: a systematic review of effects of psychotropic drugs for bipolar disorder.Microbiology (Reading, England) · 2025Pooled it
- Gastrointestinal surgery and the gut microbiome: a systematic literature review.European journal of clinical nutrition · 2021Pooled it
- Probiotic mitigates gut hypoperfusion-associated acute gastrointestinal injury in patients undergoing cardiopulmonary bypass: a randomized controlled trial.BMC medicine · 2025Trial
- Elevated postoperative IL-1β induces disorder of intestinal microenvironment and alteration of gut microbiota.Frontiers in microbiology · 2026Article
- Multidisciplinary management of acute type A aortic dissection presenting with atypical symptoms, abdominal hemorrhage, and Rh-negative blood type: a case report.Frontiers in cardiovascular medicine · 2026Article
- Clinical and financial outcomes associated with gastrointestinal complications among patients with type B aortic dissection.Surgery open science · 2025Article
- The Effects of Surface Gastrointestinal Electrical Stimulation on Gastrointestinal Function Recovery in Patients After Acute Type A Aortic Dissection Open-Heart Surgery: A Randomized, Controlled Trial.Reviews in cardiovascular medicine · 2025Article
- Efficacy of multimodal rehabilitation strategies on gastrointestinal function recovery in postoperative aortic dissection patients: a narrative review.Frontiers in physiology · 2025Review
- Clinical efficacy and mechanisms of transcutaneous auricular vagus nerve stimulation targeting the gut-brain axis for postoperative complications of aortic dissection: study protocol for a randomized controlled trial.Frontiers in medicine · 2025Article
- Gut Microbial Taxonomy and Its Role as a Biomarker in Aortic Diseases: A Systematic Review and Future Perspectives.Journal of clinical medicine · 2024Review
- StrainXpress: strain aware metagenome assembly from short reads.Nucleic acids research · 2022Article
- Pretreatment with IPA ameliorates colitis in mice: Colon transcriptome and fecal 16S amplicon profiling.Frontiers in immunology · 2022Article
- Article
- Bacterial metabolites and cardiovascular risk in children with chronic kidney disease.Molecular and cellular pediatrics · 2021Review
- Effects of Sevoflurane Inhalation Anesthesia on the Intestinal Microbiome in Mice.Frontiers in cellular and infection microbiology · 2021Article
- Bacteroides thetaiotaomicron-Infecting Bacteriophage Isolates Inform Sequence-Based Host Range Predictions.Cell host & microbe · 2020Article
- Effect of Combined Live Probiotics Alleviating the Gastrointestinal Symptoms of Functional Bowel Disorders.Gastroenterology research and practice · 2020Article
- IDO and Kynurenine Metabolites in Peripheral and CNS Disorders.Frontiers in immunology · 2020Review
- Peri-operative risk factors for in-hospital mortality in acute type A aortic dissection.Journal of thoracic disease · 2019Article
- The Role of the Small Bowel in Unintentional Weight Loss after Treatment of Upper Gastrointestinal Cancers.Journal of clinical medicine · 2019Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thoracic aortic dissection (TAAD) is one of the most common types of aortic diseases. Although surgery remains the main method of treatment, the high rate of postoperative gastrointestinal complications significantly influences the effects of surgery and the recovery process. Moreover, the mechanisms underlying this disease remain unclear. To address these problems, we examined changes in the gut microbiota in 40 thoracic aortic dissection patients with abdominal complications after surgery. Levels of white blood cells (WBC), neutrophile granulocytes (NE), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were higher in all patients after surgery. Levels of inflammatory cytokines, including interleukin (IL)-2, IL-6, IL-8, and IL-10, were also higher after surgery. A metagenome analysis revealed that levels of Oscillibacter, Anaerotruncus, Alistipes, and Clostridium difficile were higher after the operation. The abundance of functional genes, such as the spermidine/putrescine transport system permease protein, the flagellar motor switch protein, and branched-chain amino acid transport system proteins, was also higher post-surgery. These changes likely contribute to diarrhea, bloating, gastrointestinal bleeding, and other abdominal complications after surgery, and our research opens up new treatment possibilities for patients suffering from abdominal complications after surgical treatment.
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