Evidence map›Paper›PMID 29123029›Full record

ArticleThe Journal of biological chemistry2018

Phenotypic dissection of the mouse

Charlotte Buckley, Robert J Nelson, Linda J Mullins, Matthew G F Sharp, Stewart Fleming, Christopher J Kenyon, Sabrina Semprini, Dominik Steppan, Janos Peti-Peterdi, Armin Kurtz and 2 more

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Charlotte BuckleyFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom, cbuckley@exseed.ed.ac.uk.
Robert J NelsonFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
Linda J MullinsFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
Matthew G F SharpFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
Stewart Flemingthe University of Dundee, Ninewells Hospital Medical School, Dundee DD1 9SY, Scotland.
Christopher J KenyonFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
Sabrina SempriniFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
Dominik Steppanthe Physiologisches Institut der Universität Regensburg, Regensburg D-93053, Germany.
Janos Peti-Peterdithe Department of Physiology and Biophysics and Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, and.
Armin Kurtzthe Physiologisches Institut der Universität Regensburg, Regensburg D-93053, Germany.
Helen Christianthe Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom.
John J MullinsFrom the University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom, J.Mullins@ed.ac.uk.

Funding

Multiphoton Imaging of the Juxtaglomerular ApparatusR01DK064324 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JANOS PETI-PETERDI · 2004 to 2026
$8.4M
Multiphoton microscope replacement for USC shared resourceS10OD021833 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PETI-PETERDI, JANOS · 2017 to 2017
$600k
British Heart Foundation RE/08/001/23904NIDDK NIH HHS R01 DK064324NIH HHS S10 OD021833Wellcome TrustWellcome Trust WT052633MA
6 · The paper itself

Abstract

Normal renin synthesis and secretion is important for the maintenance of juxtaglomerular apparatus architecture. Mice lacking a functional

Indexed as

Genetic Complementation TestTransgenesAnimalsHumansJuxtaglomerular ApparatusMiceMice, KnockoutReninReninanimal modelconfocal microscopyelectron microscopy (EM)granulationhuman reninimmunochemistryjuxtaglomerularmacula densamousereninrenin angiotensin systemsecretiontransgenic mice

Identifiers

PMID29123029
PMCPMC5787795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.