ArticlePediatrics2017
Eating Disorders, Autoimmune, and Autoinflammatory Disease.
Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- A systematic review on the prevalence of, and risk factors for, eating disorders in systemic lupus erythematosus.Journal of health psychology · 2026Pooled it
- Polaprezinc (Zinc-L-Carnosine Complex) as an Add-on Therapy for Binge Eating Disorder and Bulimia Nervosa, and the Possible Involvement of Zinc Deficiency in These Conditions: A Pilot Study.Journal of clinical psychopharmacologyTrial
- Review
- Neuropsychological and metabolic interconnectivity in obesity, anorexia and bulimia nervosa - an integrative literature review.Metabolic brain disease · 2026Review
- Psilocybin-Assisted Therapy for Adolescent Anorexia Nervosa: Clinical Considerations and Emerging Models of Care.Current psychiatry reports · 2026Review
- Challenges in Dietary Therapy in Pediatric Eosinophilic Esophagitis (EoE)-A Narrative Review.Nutrients · 2025Review
- Avoidant and restrictive food intake disorder among children with eosinophilic esophagitis.JPGN reports · 2025Article
- Predictors of Anorexia Nervosa and Obsessive-Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort.The International journal of eating disorders · 2025Article
- Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders.Translational psychiatry · 2025Article
- Mental Ill-Health in young people with systemic autoinflammatory disease - a scoping review.Rheumatology international · 2025Article
- Preliminary Evidence That Shared Genetic Influences Underlie Comorbidity Between Self-Reported Eating and Internalizing Disorders and Gastrointestinal Disease in Adult Women and Men.The International journal of eating disorders · 2025Article
- Article
- Neurodivergence, intersectionality, and eating disorders: a lived experience-led narrative review.Journal of eating disorders · 2024Review
- Identification of State Markers in Anorexia Nervosa: Replication and Extension of Inflammation-Associated Biomarkers Using Multiplex Profiling.Biological psychiatry global open science · 2024Article
- Elevated interleukin-6 in women with binge-eating spectrum disorders.The International journal of eating disorders · 2024Article
- Long covid and mental and physical health: A cross-sectional study of adults in California.Public health challenges · 2024Article
- The importance of factors early in life for development of eating disorders in young people, with some focus on type 1 diabetes.Eating and weight disorders : EWD · 2024Article
- Cerebrospinal fluid characteristics of patients presenting for evaluation of pediatric acute-neuropsychiatric syndrome.Frontiers in behavioral neuroscience · 2024Article
- Exploring How Virtual Reality Could Be Used to Treat Eating Disorders: Qualitative Study of People With Eating Disorders and Clinicians Who Treat Them.JMIR XR and spatial computing · 2024Article
- Dysfunction of Inflammatory Pathways and Their Relationship with Anti-Hypothalamic Autoantibodies in Patients with Anorexia Nervosa.Nutrients · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
Abstract
objectivesIdentifying factors associated with risk for eating disorders is important for clarifying etiology and for enhancing early detection of eating disorders in primary care. We hypothesized that autoimmune and autoinflammatory diseases would be associated with eating disorders in children and adolescents and that family history of these illnesses would be associated with eating disorders in probands.
methodsIn this large, nationwide, population-based cohort study of all children and adolescents born in Denmark between 1989 and 2006 and managed until 2012, Danish medical registers captured all inpatient and outpatient diagnoses of eating disorders and autoimmune and autoinflammatory diseases. The study population included 930 977 individuals (48.7% girls). Cox proportional hazards regression models and logistic regression were applied to evaluate associations.
resultsWe found significantly higher hazards of eating disorders for children and adolescents with autoimmune or autoinflammatory diseases: 36% higher hazard for anorexia nervosa, 73% for bulimia nervosa, and 72% for an eating disorder not otherwise specified. The association was particularly strong in boys. Parental autoimmune or autoinflammatory disease history was associated with significantly increased odds for anorexia nervosa (odds ratio [OR] = 1.13, confidence interval [CI] = 1.01-1.25), bulimia nervosa (OR = 1.29; CI = 1.08-1.55) and for an eating disorder not otherwise specified (OR = 1.27; CI = 1.13-1.44).
conclusionsAutoimmune and autoinflammatory diseases are associated with increased risk for eating disorders. Ultimately, understanding the role of immune system disturbance for the etiology and pathogenesis of eating disorders could point toward novel treatment targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.