Evidence map›Paper›PMID 29122960›Full record

ArticlePhysiological reports2017

MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles.

Vishal A Salunkhe, Jones K Ofori, Nikhil R Gandasi, Sofia A Salö, Sofia Hansson, Markus E Andersson, Anna Wendt, Sebastian Barg, Jonathan L S Esguerra, Lena Eliasson

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

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  6. MicroRNAs, Parkinson's Disease, and Diabetes Mellitus.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Vishal A SalunkheDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Jones K OforiDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Nikhil R GandasiDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Sofia A SalöDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Sofia HanssonDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Markus E AnderssonDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Anna WendtDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden.
Sebastian BargDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Jonathan L S EsguerraDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden lena.eliasson@med.lu.se jonathan.esguerra@med.lu.se.
Lena EliassonDepartment of Clinical Sciences Malmö, Islet Cell Exocytosis Lund University Diabetes Centre Lund University, Malmö, Sweden lena.eliasson@med.lu.se jonathan.esguerra@med.lu.se.
Lund University · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs contribute to the maintenance of optimal cellular functions by fine-tuning protein expression levels. In the pancreatic

Indexed as

AnimalsCell LineDiabetes Mellitus, Type 2Disease Models, AnimalExocytosisHumansInsulinInsulin-Secreting CellsInsulin SecretionIslets of LangerhansMicroRNAsMunc18 ProteinsRatsSynaptosomal-Associated Protein 25SynaptotagminsInsulinMicroRNAsMIRN335 microRNA, humanMunc18 ProteinsSnap25 protein, ratStxbp1 protein, ratSynaptosomal-Associated Protein 25SynaptotagminsSyt11 protein, ratBeta cellexocytosisinsulin secretionmicroRNApatch‐clampSNAP25STXBP1TIRFType 2 Diabetes

Identifiers

PMID29122960
PMCPMC5688784
OpenAlexW2767354746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.