Evidence map›Paper›PMID 29122955›Full record

ArticlePhysiological reports2017

DNPEP is not the only peptidase that produces SPAK fragments in kidney.

Rainelli Koumangoye, Eric Delpire

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rainelli KoumangoyeDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee.
Eric DelpireDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee eric.delpire@vanderbilt.edu.ORCID http://orcid.org/0000-0002-3702-1599
Vanderbilt University · US

Funding

WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1M
LSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560k
NIDDK NIH HHS R01 DK093501NIH HHS S10 OD021630
6 · The paper itself

Abstract

SPAK (STE20/SPS1-related proline/alanine-rich kinase) regulates Na

Indexed as

AnimalsCRISPR-Cas SystemsFemaleGlutamyl AminopeptidaseKidneyMaleMiceMice, KnockoutPeptide HydrolasesProtein Serine-Threonine KinasesGlutamyl AminopeptidasePeptide HydrolasesProtein Serine-Threonine KinasesStk39 protein, mouseAntibody specificityCRISPR/cas9DNPEP knockoutmouse model validationproteolytic cleavageSte20p‐like kinases

Identifiers

PMID29122955
PMCPMC5688775
OpenAlexW2767613348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.