Evidence map›Paper›PMID 29122853›Full record

ArticleG3 (Bethesda, Md.)2018

Genome-Wide Screen for

Sujal S Phadke, Calum J Maclean, Serena Y Zhao, Emmi A Mueller, Lucas A Michelotti, Kaitlyn L Norman, Anuj Kumar, Timothy Y James

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Standardization ofJournal of fungi (Basel, Switzerland) · 2018
    Review
  12. Rising Into Relevance: A Rare Case ofJournal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sujal S PhadkeDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109.
Calum J MacleanDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109.
Serena Y ZhaoDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109.
Emmi A MuellerDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109.ORCID 0000-0002-7805-8785
Lucas A MichelottiDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109.
Kaitlyn L NormanDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.
Anuj KumarDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.ORCID 0000-0002-8923-297X
Timothy Y JamesDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109 tyjames@umich.edu.ORCID 0000-0002-1123-5986

Funding

Genetic screen for fungal triggers of the NLRP-3-inflammasone in macrophagesR21AI114837 · NIAID · UNIVERSITY OF ROCHESTER · PI KRYSAN, DAMIAN J, WELLINGTON, MELANIE · 2015 to 2016
$431k
How eukaryotic pathogens explore the fitness landscape by mitotic recombinationR21AI105167 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JAMES, TIM · 2013 to 2014
$428k
NIAID NIH HHS R21 AI105167NIAID NIH HHS R21 AI114837
6 · The paper itself

Abstract

Environmental opportunistic pathogens can exploit vulnerable hosts through expression of traits selected for in their natural environments. Pathogenicity is itself a complicated trait underpinned by multiple complex traits, such as thermotolerance, morphology, and stress response. The baker's yeast,

Indexed as

Genome, FungalAllelesAnimalsCell WallGene OntologyGenome-Wide Association StudyGenotypeHost-Pathogen InteractionsImmunity, InnateLarvaMitochondriaMolecular Sequence AnnotationMothsMutationPhenotypeQuantitative Trait LociTyrosinebarseqbulk segregant analysishybridpseudohyphaevirulence

Identifiers

PMID29122853
PMCPMC5765367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.