Evidence map›Paper›PMID 29122839›Full record

ArticleDevelopment (Cambridge, England)2017

FGF receptors control alveolar elastogenesis.

Rongbo Li, John C Herriges, Lin Chen, Robert P Mecham, Xin Sun

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Prenatal FGFR2 Signaling via PI3K/AKT Specifies the PDGFRAAmerican journal of respiratory cell and molecular biology · 2024
    Article
  9. Article
  10. Contribution ofeLife · 2022
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongbo LiDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
John C HerrigesLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Lin ChenDepartment of Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR), Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
Robert P MechamDepartment of Cell Biology & Physiology, Washington University School of Medicine, Saint Louis, MO 631103, USA.
Xin SunDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA xinsun@ucsd.edu.ORCID 0000-0001-8387-4966

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
ASSEMBLY OF LUNG ELASTINR37HL053325 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P. · 2000 to 2009
$4.1M
ASSEMBLY OF LUNG ELASTINR01HL053325 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P. · 1995 to 2019
$3.6M
VESSEL STIFFENING, HYPERTENSION, AND VASCULAR EXTRACELLULAR MATRIXR01HL105314 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P., WAGENSEIL, JESSICA · 2010 to 2018
$3.2M
Investigating Effects of Viral Infection on Lung DevelopmentR01HL097134 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SUN, XIN · 2009 to 2013
$2.4M
FGF Signaling in Lung Maturation and Response to InjuryR01HL113870 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SUN, XIN · 2012 to 2016
$2.1M
Respiratory Deficiencies in Congenital Diaphragmatic HerniaR01HL122406 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SUN, XIN · 2015 to 2018
$1.8M
NHLBI NIH HHS R01 HL053325NHLBI NIH HHS R01 HL097134NHLBI NIH HHS R01 HL105314NHLBI NIH HHS R01 HL113870NHLBI NIH HHS R01 HL122406NHLBI NIH HHS R37 HL053325NIGMS NIH HHS T32 GM007133
6 · The paper itself

Abstract

Alveologenesis, the final step of lung development, is characterized by the formation of millions of alveolar septa that constitute the vast gas-exchange surface area. The genetic network driving alveologenesis is poorly understood compared with earlier steps in lung development. FGF signaling through receptors

Indexed as

AnimalsContractile ProteinsEpitheliumExtracellular MatrixExtracellular Matrix ProteinsMesodermMiceMice, KnockoutOrganogenesisPulmonary AlveoliReceptor, Fibroblast Growth Factor, Type 3Receptor, Fibroblast Growth Factor, Type 4RNA Splicing FactorsSignal TransductionContractile ProteinsExtracellular Matrix ProteinsFgfr3 protein, mouseFgfr4 protein, mousemicrofibrillar proteinReceptor, Fibroblast Growth Factor, Type 3Receptor, Fibroblast Growth Factor, Type 4RNA Splicing FactorsAlveologenesisElastin extracellular matrixFGF signalingLung developmentMouse

Identifiers

PMID29122839
PMCPMC5769617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.