Evidence map›Paper›PMID 29122811›Full record

ArticleJournal of the American Heart Association2017

Comparison of Inappropriate Shocks and Other Health Outcomes Between Single- and Dual-Chamber Implantable Cardioverter-Defibrillators for Primary Prevention of Sudden Cardiac Death: Results From the Cardiovascular Research Network Longitudinal Study of Implantable Cardioverter-Defibrillators.

Pamela N Peterson, Robert T Greenlee, Alan S Go, David J Magid, Andrea Cassidy-Bushrow, Romel Garcia-Montilla, Karen A Glenn, Jerry H Gurwitz, Stephen C Hammill, John Hayes and 9 more

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Single vs. dual chamber implantable cardioverter-defibrillators or programming of implantable cardioverter-defibrillators in patients without a bradycardia pacing indication: systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2018
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Optimal Strategies to Reduce Inappropriate Implantable Cardioverter-defibrillator Shocks.The Journal of innovations in cardiac rhythm management · 2019
    Review
  11. Observational
  12. Review
  13. Considering Factors in the Single- Versus Dual-coil Lead Debate.The Journal of innovations in cardiac rhythm management · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 1 country.

Pamela N PetersonDenver Health Medical Center, Denver, CO pamela.peterson@ucdenver.edu.
Robert T GreenleeMarshfield Clinic Research Foundation, Marshfield, WI.
Alan S GoDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
David J MagidUniversity of Colorado Denver Anschutz Medical Campus, Aurora, CO.
Andrea Cassidy-BushrowDepartment of Public Health Sciences, Henry Ford Hospital, Detroit, MI.
Romel Garcia-MontillaMarshfield Clinic Research Foundation, Marshfield, WI.
Karen A GlennInstitute for Health Research, Kaiser Permanente Colorado, Denver, CO.
Jerry H GurwitzMeyers Primary Care Institute, Worcester, MA.
Stephen C HammillDivision of Cardiology, Mayo Clinic, Rochester, MN.
John HayesMarshfield Clinic Research Foundation, Marshfield, WI.
Alan KadishTouro College, New York, NY.
Kristi ReynoldsKaiser Permanente Southern California Department of Research and Evaluation, Pasadena, CA.
Param SharmaMarshfield Clinic Research Foundation, Marshfield, WI.
David H SmithKaiser Permanente Northwest Center for Health Research, Portland, OR.
Paul D VarosyUniversity of Colorado Denver Anschutz Medical Campus, Aurora, CO.
Humberto VidailletMarshfield Clinic Research Foundation, Marshfield, WI.
Chan X ZengInstitute for Health Research, Kaiser Permanente Colorado, Denver, CO.
Sharon-Lise T NormandHarvard Medical School, Boston, MA.
Frederick A MasoudiUniversity of Colorado Denver Anschutz Medical Campus, Aurora, CO.
Marshfield Clinic · USKaiser Permanente · USUniversity of Colorado Denver · USHarvard University · USHenry Ford Hospital · USKaiser Permanente Center for Health Research · USMayo Clinic in Arizona · USTouro College · USUniversity of California, San Francisco · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn US clinical practice, many patients who undergo placement of an implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death receive dual-chamber devices. The superiority of dual-chamber over single-chamber devices in reducing the risk of inappropriate ICD shocks in clinical practice has not been established. The objective of this study was to compare risk of adverse outcomes, including inappropriate shocks, between single- and dual-chamber ICDs for primary prevention. METHODS AND

resultsWe identified patients receiving a single- or dual-chamber ICD for primary prevention who did not have an indication for pacing from 15 hospitals within 7 integrated health delivery systems in the Longitudinal Study of Implantable Cardioverter-Defibrillators from 2006 to 2009. The primary outcome was time to first inappropriate shock. ICD shocks were adjudicated for appropriateness. Other outcomes included all-cause hospitalization, heart failure hospitalization, and death. Patient, clinician, and hospital-level factors were accounted for using propensity score weighting methods. Among 1042 patients without pacing indications, 54.0% (n=563) received a single-chamber device and 46.0% (n=479) received a dual-chamber device. In a propensity-weighted analysis, device type was not significantly associated with inappropriate shock (hazard ratio, 0.91; 95% confidence interval, 0.59-1.38 [

conclusionsAmong patients who received an ICD for primary prevention without indications for pacing, dual-chamber devices were not associated with lower risk of inappropriate shock or differences in hospitalization or death compared with single-chamber devices. This study does not justify the use of dual-chamber devices to minimize inappropriate shocks.

Indexed as

RegistriesAgedDeath, Sudden, CardiacDefibrillators, ImplantableEquipment DesignFemaleHeart FailureHumansIncidenceLongitudinal StudiesMaleMiddle AgedPrimary PreventionRetrospective StudiesSurvival RateTreatment Outcomedefibrillator shocksimplantable cardioverter‐defibrillatorsoutcomes research

Identifiers

PMID29122811
PMCPMC5721776
OpenAlexW2767448569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.