Evidence map›Paper›PMID 29122756›Full record

Trial reportBlood2018

FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy.

Anja Mottok, Vindi Jurinovic, Pedro Farinha, Andreas Rosenwald, Ellen Leich, German Ott, Heike Horn, Wolfram Klapper, Michael Boesl, Wolfgang Hiddemann and 7 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Pediatric-type follicular lymphoma: a short review.International journal of hematologic oncology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Novel markers in pediatric-type follicular lymphoma.Virchows Archiv : an international journal of pathology · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Anja MottokCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.ORCID 0000-0003-3125-0494
Vindi JurinovicMedical Department III, University Hospital, and.
Pedro FarinhaCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.ORCID 0000-0001-9364-9391
Andreas RosenwaldInstitute of Pathology, University of Würzburg and Comprehensive Cancer Centre Mainfranken, Würzburg, Germany.
Ellen LeichInstitute of Pathology, University of Würzburg and Comprehensive Cancer Centre Mainfranken, Würzburg, Germany.ORCID 0000-0002-2461-8070
German OttDepartment of Clinical Pathology, Robert Bosch Hospital, Stuttgart, Germany.ORCID 0000-0001-7990-6793
Heike HornDr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
Wolfram KlapperDepartment of Pathology, Hematopathology Section and Lymph Node Registry, University Kiel, Kiel, Germany; and.
Michael BoeslMedical Department III, University Hospital, and.
Wolfgang HiddemannMedical Department III, University Hospital, and.
Christian SteidlCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.ORCID 0000-0001-9842-9750
Joseph M ConnorsCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.ORCID 0000-0002-1361-7531
Laurie H SehnCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.
Randy D GascoyneCentre for Lymphoid Cancer, BC Cancer Agency, Vancouver, BC, Canada.ORCID 0000-0002-2610-5690
Eva HosterMedical Department III, University Hospital, and.
Oliver WeigertMedical Department III, University Hospital, and.ORCID 0000-0002-0987-7373
Robert KridelDivision of Medical Oncology and Hematology, Princess Margaret Cancer Centre-University Health Network, Toronto, ON, Canada.ORCID 0000-0003-0287-7124
BC Cancer Agency · CAUniversity of Würzburg · DEZimmer Biomet (Germany) · DEChristian-Albrechts-Universität zu Kiel · DEDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology · DERobert Bosch Hospital · DEUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular lymphoma (FL) is a clinically and molecularly highly heterogeneous disease, yet prognostication relies predominantly on clinical tools. We recently demonstrated that integration of mutation status of 7 genes, including

Indexed as

Gene Expression Regulation, NeoplasticAntineoplastic Agents, ImmunologicalAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinEnhancer of Zeste Homolog 2 ProteinForkhead Transcription FactorsHumansLymphoma, FollicularMEF2 Transcription FactorsMiddle AgedMutationPrednisolonePrednisonePrognosisRepressor ProteinsAntineoplastic Agents, ImmunologicalCyclophosphamideDoxorubicinEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanForkhead Transcription FactorsFOXP1 protein, humanMEF2B protein, humanMEF2 Transcription FactorsPrednisolonePrednisoneR-CVP protocolRepressor ProteinsRituximabVincristine

Identifiers

PMID29122756
PMCPMC5757687
OpenAlexW2767633842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.