Evidence map›Paper›PMID 29121205›Full record

ArticleAmerican journal of epidemiology2017

Pregnancy and Lifetime Exposure to Fine Particulate Matter and Infant Mortality in Massachusetts, 2001-2007.

Ji-Young Son, Hyung Joo Lee, Petros Koutrakis, Michelle L Bell

Abstract read
In one paragraph

Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The GenusLife (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Association between fine particulate matter (PMEnvironmental epidemiology (Philadelphia, Pa.) · 2024
    Article
  6. Article
  7. Article
  8. Association between Long-Term Ambient PM2.5 Exposure and under-5 Mortality: A Scoping Review.International journal of environmental research and public health · 2023
    Article
  9. Article
  10. Article
  11. Understanding the Pathways from Prenatal and Post-Birth PMInternational journal of environmental research and public health · 2021
    Observational
  12. Ambient Air Pollution and Sudden Infant Death Syndrome in Korea: A Time-Stratified Case-Crossover Study.International journal of environmental research and public health · 2019
    Article
  13. Greenspace and Infant Mortality in Philadelphia, PA.Journal of urban health : bulletin of the New York Academy of Medicine · 2019
    Article
  14. Particulate Matter Mortality Rates and Their Modification by Spatial Synoptic Classification.International journal of environmental research and public health · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ji-Young SonSchool of Forestry and Environmental Studies, Yale University, Connecticut.
Hyung Joo LeeCalifornia Air Resources Board, California Environmental Protection Agency, Sacramento, California.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Massachusetts.
Michelle L BellSchool of Forestry and Environmental Studies, Yale University, Connecticut.

Funding

Effects of Fine Particle Composition on Birth OutcomesR01ES019587 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2011 to 2015
$2.6M
NIEHS NIH HHS R01 ES019587
6 · The paper itself

Abstract

Many studies have found associations between particulate matter having an aerodynamic diameter of ≤2.5 μm (PM2.5) and adult mortality. Comparatively few studies evaluated particles and infant mortality, although infants and children are particularly vulnerable to pollution. Moreover, existing studies mostly focused on short-term exposure to larger particles. We investigated PM2.5 exposure during pregnancy and lifetime and postneonatal infant mortality. The study included 465,682 births with 385 deaths in Massachusetts (2001-2007). Exposures were estimated from PM2.5-prediction models based on satellite imagery. We applied extended Cox proportional hazards modeling with time-dependent covariates to total, respiratory, and sudden infant death syndrome mortality. Exposure was calculated from birth to death (or end of eligibility for outcome, at age 1 year) and pregnancy (gestation and each trimester). Models adjusted for sex, birth weight, gestational length, season of birth, temperature, relative humidity, and maternal characteristics. Hazard ratios for total, respiratory, and sudden infant death syndrome mortality per-interquartile-range increase (1.3 μg/m3) in lifetime PM2.5 exposure were 2.66 (95% confidence interval (CI): 2.11, 3.36), 3.14 (95% CI: 2.39, 4.13), and 2.50 (95% CI: 1.56, 4.00), respectively. We did not observe a statistically significant relationship between gestational exposure and mortality. Our findings provide supportive evidence that lifetime exposure to PM2.5 increases risk of infant mortality.

Indexed as

Infant MortalityAdultEducational StatusEnvironmental ExposureFemaleHumansInfantInfant, NewbornMaleMarital StatusMassachusettsMaternal AgeMaternal ExposureParticulate MatterPregnancyProportional Hazards ModelsParticulate Matterfine particulate mattergestationinfant mortalitylifetimePM2.5

Identifiers

PMID29121205
PMCPMC5860580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.