Evidence map›Paper›PMID 29120959›Full record

ArticleJournal of hypertension2018

Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China.

Mengyu Fan, Canqing Yu, Yu Guo, Zheng Bian, Xia Li, Ling Yang, Yiping Chen, Mingqiang Li, Xianzhi Li, Junshi Chen and 4 more

Abstract read
In one paragraph

Article in Journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Article
  5. Genetic Background of Acute Heart Rate Response to Exercise.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Influencing Factors on Cardiovascular Health in China.Journal of geriatric cardiology : JGC · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mengyu FanDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center.
Canqing YuDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center.
Yu GuoChinese Academy of Medical Sciences, Beijing, China.
Zheng BianChinese Academy of Medical Sciences, Beijing, China.
Xia LiDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center.
Ling YangClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Yiping ChenClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Mingqiang LiLiuzhou Center for Disease Control and Prevention.
Xianzhi LiLiuyang Center for Disease Control and Prevention, Liuyang.
Junshi ChenChina National Center for Food Safety Risk Assessment, Beijing, China.
Zhengming ChenClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Jun LvDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center.
Liming LiDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center.
China Kadoorie Biobank Collaborative Group

Funding

Medical Research Council MC_U137686851Medical Research Council MC_UU_12026/2Wellcome Trust 088158/Z/09/ZWellcome Trust 104085/Z/14/ZWellcome Trust 212946/Z/18/Z
6 · The paper itself

Abstract

objectivesWe aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults.

methodsWe performed a prospective cohort study in 150 391 hypertensive participants aged 30-79 years from the China Kadoorie Biobank study of 512 891 participants recruited from 10 diverse areas across China during 2004-2008. Participants with heart disease, stroke, chronic obstructive pulmonary disease, and cancer at baseline were excluded.

resultsDuring 1069 863 person-years of follow-up (median 7.1 years), a total of 5332 men and 4384 women died. Compared with hypertensive participants in the lowest level of total physical activity, the hazard ratios for all-cause mortality were 0.80 (0.76-0.84), 0.69 (0.65-0.73), and 0.67 (0.62-0.72) for those in quartiles 2-4 (Ptrend < 0.001), respectively. Inverse associations were also observed for cardiovascular mortality. Being active in occupational, domestic, and leisure time were associated with lower risk of all-cause and cardiovascular mortality. However, the adjusted ratio for active commuting was 1.08 (1.02-1.15) for all-cause mortality. High levels of low-intensity, moderate-intensity, and vigorous-intensity physical activity were consistently associated with lower risks of all-cause and cardiovascular mortality.

conclusionAmong Chinese hypertensive adults, a higher level of physical activity reduces all-cause and cardiovascular mortality, independent of intensities of physical activity. Not only leisure-time but also occupational and domestic physical activities were benefited.

Indexed as

Cause of DeathExercisePhysical ExertionAdultAgedCardiovascular DiseasesChinaFemaleHumansHypertensionLeisure ActivitiesMaleMiddle AgedOccupationsProportional Hazards ModelsProspective Studies

Identifiers

PMID29120959
PMCPMC5862003

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.