ArticleCancer epidemiology2017
Risk factors for breast cancer in the breast cancer risk model study of Guam and Saipan.
Article in Cancer epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Effect of breastfeeding on the risk of breast cancer: a meta-analysis of observational studies.International breastfeeding journal · 2026Pooled it
- The relationship between central obesity and risk of breast cancer: a dose-response meta-analysis of 7,989,315 women.Frontiers in nutrition · 2023Pooled it
- The Association of Cardiometabolic Risk Factors in Parent-Child Dyads in Guam: Pacific Islands Cohort on Cardiometabolic Health Study.International journal of environmental research and public health · 2025Article
- Breast cancer incidence and stage at diagnosis in the six US-Affiliated Pacific Islands.Cancer epidemiology · 2024Article
- Traditional and new lifestyle interventions to prevent breast cancer recurrence (TANICA): a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- Prediction of breast cancer risk among women of the Mariana Islands: the BRISK retrospective case-control study.BMJ open · 2022Article
- A review of menopause nomenclature.Reproductive health · 2022Review
- Risk factors assessment of breast cancer among Iraqi Kurdish women: Case-control study.Journal of family medicine and primary care · 2019Article
- Vitex Rotundifolia Fractions Induced Apoptosis in Human Breast Cancer T-47D Cell Line via Activation of Extrinsic and Intrinsic Pathway.Asian Pacific journal of cancer prevention : APJCP · 2019Article
- Article
- Modeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study.Cancer management and research · 2019Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundChamorro Pacific Islanders in the Mariana Islands have breast cancer incidence rates similar to, but mortality rates higher than, those of U.S. women. As breast cancer risk factors of women of the Mariana Islands may be unique because of ethnic and cultural differences, we studied established and suspected risk factors for breast cancer in this unstudied population.
methodsFrom 2010-2013, we conducted retrospective case-control study of female breast cancer (104 cases and 185 controls) among women in the Mariana Islands. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for each of various lifestyle-related factors from logistic regression of breast cancer, in all women and in pre- and postmenopausal women separately. Tests for interaction of risk factors with ethnicity were based on the Wald statistics for cross-product terms.
resultsOf the medical and reproductive factors considered - age at menarche, breastfeeding, number of live births, age at first live birth, hormone use, and menopause - only age at first live birth was confirmed. Age at first live birth, among parous women, was higher among cases (mean 24.9 years) than controls (mean 23.2 years); with increased breast cancer risk (OR=2.53; 95% CI, 1.04-6.19 for age≥30y compared to <20y, P for trend=0.01). Of the lifestyle factors -body mass index, waist circumference, physical activity, alcohol and betel-nut intake, and education - only waist circumference (OR=1.65; 95% CI 0.87-3.14 for the highest tertile group compared to the lowest, P for trend=0.04) was significantly associated with breast cancer risk and only in Filipino women. The association with many other established risk factors, such as BMI, hormone use and physical activity, were in the expected direction but were not significant. Associations for family history of breast cancer and alcohol intake were not evident
conclusionsThe results provide a basis for cancer prevention guidance for women in the Mariana Islands.
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