Evidence map›Paper›PMID 29120813›Full record

ArticleClinical imaging

Visibility of mammographically occult breast cancer on diffusion-weighted MRI versus ultrasound.

Nita Amornsiripanitch, Habib Rahbar, Averi E Kitsch, Diana L Lam, Brett Weitzel, Savannah C Partridge

Abstract readComparative Study
In one paragraph

Article in Clinical imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Breast Diffusion-weighted MR Imaging: Current Applications, Insights from Screening, and Future Directions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  4. Occult breast cancer in an older woman: A case report.Experimental and therapeutic medicine · 2025
    Article
  5. Non-contrast Breast MR Imaging.Radiologic clinics of North America · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nita AmornsiripanitchBreast Imaging, University of Massachusetts Memorial Medical Center, United States.
Habib RahbarDepartment of Radiology, University of Washington, Seattle, WA, United States.
Averi E KitschDepartment of Radiology, University of Washington, Seattle, WA, United States.
Diana L LamDepartment of Radiology, University of Washington, Seattle, WA, United States.
Brett WeitzelDepartment of Radiology, University of Washington, Seattle, WA, United States.
Savannah C PartridgeDepartment of Radiology, University of Washington, Seattle, WA, United States. Electronic address: scp3@uw.edu.

Funding

Validation and Standardization of the Apparent Diffusion Coefficient as a Quantitative Imaging Biomarker in Breast CancerR01CA207290 · NCI · UNIVERSITY OF WASHINGTON · PI PARTRIDGE, SAVANNAH CORRINA · 2017 to 2022
$2.2M
MR Diffusion Tensor Imaging for Detection and Characterization of Breast LesionsR01CA151326 · NCI · UNIVERSITY OF WASHINGTON · PI PARTRIDGE, SAVANNAH CORRINA · 2010 to 2014
$1.3M
NCI NIH HHS R01 CA151326NCI NIH HHS R01 CA207290
6 · The paper itself

Abstract

purposeTo investigate the visibility of mammographically occult breast cancers on diffusion-weighted MRI (DWI) versus ultrasound. MATERIALS AND

methodsMammographically occult breast cancers (n=60) initially detected on contrast-enhanced MRI that underwent pre-biopsy targeted ultrasound were retrospectively evaluated for visibility on DWI and ultrasound.

resultsMore cancers were visible on DWI than ultrasound (78% vs. 63%; p=0.049), with 32 (53%) visible on both and 7 (12%) not visible on either. Visibility differences were more significant in larger lesions (92% vs. 68%, p=0.006).

conclusionDWI may detect more mammographically occult cancers than ultrasound, warranting further investigation as an alternative supplemental screening technique.

Indexed as

MammographyAdultAgedBiopsyBreastBreast NeoplasmsContrast MediaDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingMiddle AgedNeoplasms, Unknown PrimaryRetrospective StudiesUltrasonographyYoung AdultContrast MediaBreast cancerDiffusion-weighted MRI (DWI)Dynamic contrast-enhanced MRI (DCE-MRI)Supplemental screeningUltrasound

Identifiers

PMID29120813
PMCPMC5924642

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.