Evidence map›Paper›PMID 29120735›Full record

ReviewCurrent opinion in genetics & development2017

The rewiring of transcription circuits in evolution.

Alexander D Johnson

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. The Origin and Early Evolution of Fungi: Challenges, Inferences, and Principles.Annual review of cell and developmental biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. A recently evolved TAF8 isoform arising from anbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Molecular model of a bacterial flagellar motorbioRxiv : the preprint server for biology · 2024
    Article
  14. Review
  15. Article
  16. eLife · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alexander D JohnsonDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, United States. Electronic address: ajohnson@cgl.ucsf.edu.

Funding

MECHANISMS OF YEAST TRANSCRIPTIONAL REGULATORSR01GM037049 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 1986 to 2024
$9.4M
NIGMS NIH HHS R01 GM037049
6 · The paper itself

Abstract

The binding of transcription regulators to cis-regulatory sequences is a key step through which all cells regulate expression of their genes. Due to gains and losses of cis-regulatory sequences and changes in the transcription regulators themselves, the binding connections between regulators and their target genes rapidly change over evolutionary time and constitute a major source of biological novelty. This review covers recent work, carried out in a wide range of species, that addresses the overall extent of these evolutionary changes, their consequences, and some of the molecular mechanisms that lie behind them.

Indexed as

Evolution, MolecularTranscription, GeneticGene Expression Regulation

Identifiers

PMID29120735
PMCPMC6901287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.