ReviewJournal of perinatology : official journal of the California Perinatal Association2018
Manipulating the microbiome: evolution of a strategy to prevent S. aureus disease in children.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Association of Neonatal and Maternal Nasal Microbiome Among Neonates in the Intensive Care Unit.Open forum infectious diseases · 2024Article
- Article
- Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Late-Onset Sepsis Among Very Preterm Infants.Pediatrics · 2022Observational
- Altering Microbiomes with Hydroxyapatite Nanoparticles: A Metagenomic Analysis.Materials (Basel, Switzerland) · 2022Article
- Article
- Challenges for Clinical Development of Vaccines for Prevention of Hospital-Acquired Bacterial Infections.Frontiers in immunology · 2020Review
- The Association Between the Developing Nasal Microbiota of Hospitalized Neonates andOpen forum infectious diseases · 2019Article
- WHAM!: a web-based visualization suite for user-defined analysis of metagenomic shotgun sequencing data.BMC genomics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Hospitalized infants have the highest rates of invasive Staphylococcus aureus disease of any population and infection control strategies such as decolonization have been insufficient. For decades, researchers began studying the microbiome in search of new prevention strategies. The resident microbiota was found to be closely associated with susceptibility and at times, resistance to S. aureus colonization. The evolution of nucleic acid based techniques has enhanced our understanding of the complex relationship between the nasal microbiota and S. aureus colonization. We review what is known about bacterial communities in the nasal cavity of infants and discuss how future microbiome studies may help identify novel interventions to protect high-risk infants from S. aureus disease.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.