Observational studyJournal of perinatology : official journal of the California Perinatal Association2018
Vascular aging and cardiac maladaptation in growth-restricted preterm infants.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis.American journal of physiology. Heart and circulatory physiology · 2024Pooled it
- Hippocampal growth and function are reduced in the newborn following fetal growth restriction.Brain : a journal of neurology · 2026Article
- Brain sparing in fetal growth restriction: The double-edged sword of fetal hypoxaemia.The Journal of physiology · 2026Review
- Progress in cell therapies for neonatal conditions: Proceedings of the Third Neonatal Cell Therapies Symposium (2025).Pediatric research · 2026Article
- Antenatal melatonin for cardiovascular deficits in fetal growth restriction.The Journal of physiology · 2026Article
- Does Antenatal Lactoferrin Protect Hippocampal Development in Ovine Fetuses with Growth Restriction?Cells · 2025Article
- Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates.The Journal of physiology · 2025Review
- Transitional haemodynamic profiles of intrauterine growth-restricted preterm infants: correlation with antenatal Doppler characteristics.Pediatric research · 2025Article
- Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function.Brain pathology (Zurich, Switzerland) · 2025Article
- The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.Antioxidants (Basel, Switzerland) · 2024Review
- Molecular regulators of defective placental and cardiovascular development in fetal growth restriction.Clinical science (London, England : 1979) · 2024Review
- Phenotype of early-onset fetal growth restriction in sheep.Frontiers in endocrinology · 2024Article
- Does fetal growth restriction induce neuropathology within the developing brainstem?The Journal of physiology · 2023Review
- The left ventricle in well newborns versus those with perinatal asphyxia, haemodynamically significant ductus arteriosus or fetal growth restriction.Translational pediatrics · 2023Review
- Left ventricular dysfunction in the newborn.Translational pediatrics · 2023Article
- COVID-19 and Placental Infection: Are Fetal Survivors at Risk of Long-Term Cardiovascular Complications?Cureus · 2023Article
- Current Strategies to Optimize Nutrition and Growth in Newborns and Infants with Congenital Heart Disease: A Narrative Review.Journal of clinical medicine · 2022Review
- Cardiovascular and Cerebrovascular Implications of Growth Restriction: Mechanisms and Potential Treatments.International journal of molecular sciences · 2021Review
- An Overview of Vascular Dysfunction and Determinants: The Case of Children of African Ancestry.Frontiers in pediatrics · 2021Review
- Fetal Growth Restriction and Hypertension in the Offspring: Mechanistic Links and Therapeutic Directions.The Journal of pediatrics · 2020Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess arterial morphology and mechanics in preterm infants with fetal growth restriction (FGR) compared with those appropriate for gestational age (AGA) in the early neonatal period. STUDY
designThis observational study involved 20 preterm FGR infants (28 to 32 weeks) of gestational age (GA) and birth weight (BW) <10th centile and 20 preterm AGA infants. Vascular ultrasound was performed to measure aortic properties.
resultsGA and BW of FGR and AGA infants were 29.8±1.3 vs 30±0.9 weeks (P=0.78) and 923.4±168 vs 1403±237 g (P<0.001), respectively. At 10.5±1.3 (s.d.) days after birth, blood pressure (systolic 51±3 vs 46±4 mm Hg, P<0.001) and maximum aorta intima-media thickness (621±76 vs 479±54 μm; P<0.001) were significantly higher in FGR infants. Arterial wall stiffness and peripheral resistance were also increased in the FGR infants (2.36±0.24 vs 2.14±0.24, P=0.008 and 22.2±5 vs 13.7±2.3 mm Hg min ml
conclusionMaladaptive arterial-ventricular coupling was noted. Early detection may aid in early therapeutic strategies such as afterload reduction.
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