Evidence map›Paper›PMID 29120450›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Apnea, bradycardia and desaturation spells in premature infants: impact of a protocol for the duration of 'spell-free' observation on interprovider variability and readmission rates.

P Chandrasekharan, M Rawat, A M Reynolds, K Phillips, S Lakshminrusimha

Abstract readEvaluation Study
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Variation in NICU utilization: a narrative review and path forward.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  2. Article
  3. Article
  4. Incidence and Parental Perception of Cardiorespiratory Monitor Use in Preterm Infants.Journal of clinical psychology in medical settings · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Implementing point of care ultrasound in the neonatal intensive care unit: a safety study.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Observational
  9. Article
  10. Article
  11. Article
  12. A family of NICU graduates!Pediatric research · 2018
    Article
  13. Discharge without alarm(s)!Journal of perinatology : official journal of the California Perinatal Association · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

P ChandrasekharanDivision of Neonatology, Department of Pediatrics, UBMD, Women and Children's Hospital of Buffalo, John R. Oishei Children's Hospital, Buffalo, NY, USA.
M RawatDivision of Neonatology, Department of Pediatrics, UBMD, Women and Children's Hospital of Buffalo, John R. Oishei Children's Hospital, Buffalo, NY, USA.
A M ReynoldsDivision of Neonatology, Department of Pediatrics, UBMD, Women and Children's Hospital of Buffalo, John R. Oishei Children's Hospital, Buffalo, NY, USA.
K PhillipsKaleida Health, Women and Children's Hospital of Buffalo, John R. Oishei Children's Hospital, Buffalo, NY, USA.
S LakshminrusimhaDivision of Neonatology, Department of Pediatrics, UBMD, Women and Children's Hospital of Buffalo, John R. Oishei Children's Hospital, Buffalo, NY, USA.
Women & Children's Hospital of Buffalo · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Developmental Impact of NICU Exposures (DINE)UG3OD023320 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ASCHNER, JUDY LYNN, TEITELBAUM, SUSAN L · 2016 to 2017
$6.1M
Optimal Oxygenation in Neonatal Lung InjuryR01HD072929 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Satyanarayana Lakshminrusimha · 2012 to 2026
$5.4M
NCATS NIH HHS UL1 TR001412NICHD NIH HHS R01 HD072929NIH HHS UG3 OD023320
6 · The paper itself

Abstract

objectiveTo study the impact of implementing a protocol to standardize the duration of observation in preterm infants with apnea/bradycardia/desaturation spells before hospital discharge on length of stay (LOS) and readmission rates. STUDY

designA protocol to standardize the duration of in-hospital observation for preterm infants with apnea, bradycardia and desaturation spells who were otherwise ready for discharge was implemented in December 2013. We evaluated the impact of this protocol on the LOS and readmission rates of very low birth weight infants (VLBW). Data on readmission for apnea and an apparent life-threatening event (ALTE) within 30 days of discharge were collected. The pre-implementation epoch (2011 to 2013) was compared to the post-implementation period (2014 to 2016).

resultsThere were 426 and 368 VLBW discharges before and after initiation of the protocol during 2011 to 2013 and 2014 to 2016, respectively. The LOS did not change with protocol implementation (66±42 vs 64±42 days before and after implementation of the protocol, respectively). Interprovider variability on the duration of observation for apneic spells (F-8.8, P=0.04) and bradycardia spells (F-17.4, P<0.001) decreased after implementation of the protocol. The readmission rate for apnea/ALTE after the protocol decreased from 12.1 to 3.4% (P=0.01).

conclusionImplementing an institutional protocol for VLBW infants to determine the duration of apnea/bradycardia/ desaturation spell-free observation period as recommended by the American Academy of Pediatrics clinical report did not prolong the LOS but effectively reduced interprovider variability and readmission rates.

Indexed as

ApneaBenchmarkingBradycardiaFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightLength of StayMalePatient ReadmissionSeverity of Illness Index

Identifiers

PMID29120450
PMCPMC5775039
OpenAlexW2767709146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.