ArticleJournal of nephrology2018
Higher prevalence of unrecognized kidney disease at high altitude.
Article in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prevalence of metabolic syndrome and its components according to altitude levels: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Prevalence of hypertension and its relationship with altitude in highland areas: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Pooled it
- Diagnostic Criteria for Metabolic Syndrome in High-Altitude Regions: A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Renal Physiological Adaptation to High Altitude: A Systematic Review.Frontiers in physiology · 2020Pooled it
- Altitude-Related Laboratory Changes and a Novel Hemoglobin Estimation Model: A Retrospective Analysis in Children and Adults.International journal of laboratory hematology · 2026Article
- Optimized Open-Source Setting for Subjecting Rodents to Chronic Normobaric Hypoxia in Facilities with Minimal Nitrogen Supply.Life (Basel, Switzerland) · 2026Article
- External validation of a nomogram for predicting tubulointerstitial lesions in IgA nephropathy: a cross-regional study in China.Clinics (Sao Paulo, Brazil) · 2026Article
- Incidence and risk factors of acute kidney injury among neurocritical patients in high-altitude regions: a retrospective cohort study.Frontiers in medicine · 2026Article
- High altitude renal syndrome: four elements or one source?Renal failure · 2025Review
- A J-shaped relationship between hemoglobin levels and chronic kidney disease.Scientific reports · 2025Article
- Serum metabolomic profiling uncovered metabolic shifts in individuals upon moderate-altitude exposure and identified the potentiality of beta-alanine to ameliorate hyperuricemia.Redox biology · 2025Article
- The impact of high altitude (hypobaric hypoxia) on insulin resistance in humans.Journal of physiology and biochemistry · 2025Review
- Rewiring of Uric Acid Metabolism in the Intestine Promotes High-Altitude Hypoxia Adaptation in Humans.Molecular biology and evolution · 2024Article
- The benefits of early continuous renal replacement therapy in critically ill patients with acute kidney injury at high-altitude areas: a retrospective multi-center cohort study.Scientific reports · 2023Article
- Risk factors for microalbuminuria in adult Tibetan patients with high-altitude pulmonary hypertension: a cross-sectional study.Cardiovascular diagnosis and therapy · 2023Article
- Role of Arginase-II in Podocyte Injury under Hypoxic Conditions.Biomolecules · 2022Article
- Where do you live and what do you do? Two questions that might impact your kidney health.Frontiers in nephrology · 2022Review
- Effects of high altitude on renal physiology and kidney diseases.Frontiers in physiology · 2022Review
- Prevalence of and risk factors for high-altitude hyperuricaemia in Bai individuals: a cross-sectional study.The Journal of international medical research · 2021Article
- Different Expressions of HIF-1α and Metabolism in Brain and Major Visceral Organs of Acute Hypoxic Mice.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundHigh altitude renal syndrome has been described in populations with excessive erythrocytosis. We evaluated whether high altitude (HA) dwellers might be at increased risk for kidney disease.
methodsWe performed a cross-sectional study to investigate differences in prevalence of kidney function and metabolic syndrome in healthy subjects living at HA vs. sea level (SL) without any known history of hypertension, diabetes or chronic kidney disease.
resultsWe examined 293 subjects, aged 40 to 60 years: 125 SL (154 m) and 168 HA (3640 m) dwellers. HA dwellers had higher serum creatinine, lower estimated glomerular function rate (eGFR) (69.5 ± 15.2 vs. 102.1 ± 17.8 ml/min/1.73 m
conclusionsDwellers at high altitude who are considered healthy have worse kidney function, a higher prevalence of proteinuria and a lower prevalence of metabolic syndrome compared to people living at SL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.