ArticleIndian journal of pediatrics2018
Socio-demographic Profile and Economic Burden of Treatment of Transfusion Dependent Thalassemia.
Article in Indian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 35 citations in OpenAlex.
- Role of Family Dynamics in Shaping Coping Strategies Among Children with Transfusion-Dependent Thalassemia.Indian pediatrics · 2026Article
- Direct and indirect medical costs associated with transfusion-dependent beta-thalassemia in Brazil, Thailand, and India.Therapeutic advances in hematology · 2026Article
- The direct costs of transfusion-dependent beta-thalassemia in Saudi Arabia: A cost of illness analysis study.Medicine · 2025Article
- Mutation Analysis for Hemoglobinopathies in Eastern Jharkhand.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Global Globin Network and adopting genomic variant database requirements for thalassemia.Database : the journal of biological databases and curation · 2024Article
- Systematic literature review of the indirect costs and humanistic burden of β-thalassemia.Therapeutic advances in hematology · 2024Review
- Economic Evaluation of Nucleic Acid Testing for Screening of Blood Donations for Thalassemia Patients (ECONAT) in Western India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023Article
- Safety and Efficacy of Thalidomide and Hydroxyurea Combination in Beta Thalassemia Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023Article
- Healthcare resource utilization and direct costs of transfusion-dependent thalassemia patients in Dubai, United Arab Emirates: a retrospective cost-of-illness study.BMC health services research · 2022Article
- Economic burden in the management of transfusion-dependent thalassaemia patients in Malaysia from a societal perspective.Orphanet journal of rare diseases · 2021Article
- Genomics of rare genetic diseases-experiences from India.Human genomics · 2019Review
- Economic Burden of Transfusion Dependent Thalassemia.Indian journal of pediatrics · 2018Review
- Financial Burden of Treatment of Transfusion Dependent Thalassemia.Indian journal of pediatrics · 2018Article
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2 authors at 1 institution in 1 country.
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Abstract
objectiveTo compile the socio-demographic profile and estimate the economic burden of transfusion dependent thalassemia.
methodsThis cross-sectional descriptive study was conducted at a tertiary care hospital in north India. Transfusion dependent thalassemia patients on regular blood transfusion for at least a year were selected. Thalassemia diagnosis was based on HPLC and/or mutation analysis results. Clinical and laboratory parameters were collected from electronic health records. Information regarding socio-economic profile and costs incurred, including indirect costs were collected by interviewing patients' guardians. The data was analyzed as a whole cohort and also in subgroups based on age.
resultsThe data of 261 patients with a median age of 127 mo was collected. The median age at diagnosis was 9.8 mo. The total treatment expenses of a patient per year ranged from US$ 629 (INR 41,514) to US$ 2300 (INR 151,800), in the different age groups, at an average of US$ 1135 (INR 74,948). More than half (53%) of this was spent on medications. On an average, 38.8% of the family income was spent on the treatment of a thalassemia patient annually. Only 19 of 262 cases had an average pre-BT Hb ≥ 9 g/dl and serum ferritin ≤1500 ng/dl.
conclusionsThe treatment for transfusion dependent thalassemia is costly and mostly borne by the families in India. This study provides a realistic magnitude of this burden and will be useful in planning a thalassemia management program at the state or national level.
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