Evidence map›Paper›PMID 29119373›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Additional value of systolic wall thickening in myocardial stunning evaluated by stress-rest gated perfusion SPECT.

Alberto Bestetti, Besart Cuko, Adriano Decarli, Alessio Galli, Federico Lombardi

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Prognostic value of absent left ventricular ejection fraction reserve with regadenoson SPECT MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Impact of early post-stressThe international journal of cardiovascular imaging · 2021
    Article
  4. Auxiliary ischemic markers, the role of left ventricular dyssynchrony.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  5. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Single-photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  6. Stunned and Hibernating Myocardium: Where Are We Nearly 4 Decades Later?Journal of the American Heart Association · 2020
    Review
  7. Better characterization of dipyridamole-induced myocardial stunning by systolic wall thickening. A gated perfusion SPECT study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  8. Systolic wall thickening and prone acquisition as tools to reduce false positives in the interpretation of the SPECT myocardial perfusion study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  9. Myocardial stunning by gated SPECT: An old tool reinvented in a stunning turn.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alberto BestettiDepartment of Clinical and Biomedical Sciences, University of Milan, Milan, Italy.
Besart CukoSchool of Specialty in Nuclear Medicine, University of Milan, Milan, Italy.
Adriano DecarliDepartment of Clinical and Community Sciences, University of Milan, Milan, Italy.
Alessio GalliCardiovascular Diseases Unit, IRCCS Ca' Granda Major Hospital of Milan, University of Milan, Milan, Italy. aleg170389@gmail.com.
Federico LombardiCardiovascular Diseases Unit, IRCCS Ca' Granda Major Hospital of Milan, University of Milan, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim and patientsThe aim of the present study is to evaluate the additional value of systolic wall thickening to myocardial perfusion in diagnosing myocardial stunning in patients with angiography proven coronary artery disease. We selected 91 ischemic patients (82 males; mean age 59.7 ± 10.3) with CAD documented by angiography. Ischemia was defined as a summed difference score ≥5. All patients underwent a 2-day gated perfusion SPECT protocol. The patients received a dose of 740 MBq of

resultsThe post-stress LVEF was significantly lower than rest LVEF (48.1% ± 10.3% vs 50.3% ± 10.7%; P = .0001). The wall thickening summed difference score was 4.44 ± 4.13 (P = .0001). At a multivariate regression analysis, only WT-SDS as independent variable was significantly correlated with myocardial ischemia (SDS). We also divided patients according to SDS in those with mild (SDS < 8) and severe (SDS ≥ 8) ischemia. WT-SDS, but not ∆LVEF, was significantly different between groups.

conclusionsWT-SDS, more than the depression in the global function (∆LVEF) of the left ventricle, correlates with the degree of ischemia and better identifies, when present, the stunning phenomenon.

Indexed as

Exercise TestGated Blood-Pool ImagingTomography, Emission-Computed, Single-PhotonAgedCoronary Artery DiseaseCoronary CirculationFemaleHumansMaleMiddle AgedMyocardial StunningPredictive Value of TestsStroke Volumecardiac single-photon emission computed tomographyCoronary artery diseaseischemic heart diseasemyocardial stunning

Identifiers

PMID29119373
OpenAlexW2767516141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.