Evidence map›Paper›PMID 29119127›Full record

ArticleBio-protocol2016

Sensitive Assessment of Hippocampal Learning Using Temporally Dissociated Passive Avoidance Task.

Andrew L Eagle, Hongbing Wang, Alfred J Robison

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 75 citations in OpenAlex.

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  11. Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
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  14. Evaluation of the Effect of Cariprazine on Memory and Cognition in Experimental Rodent Models.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew L EagleDepartment of Physiology and Neuroscience Program, Michigan State University, East Lansing, USA.
Hongbing WangDepartment of Physiology and Neuroscience Program, Michigan State University, East Lansing, USA.
Alfred J RobisonDepartment of Physiology and Neuroscience Program, Michigan State University, East Lansing, USA.
Michigan State University · US

Funding

MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGYT32ES007255 · NIEHS · MICHIGAN STATE UNIVERSITY · PI JOHN J LAPRES · 1989 to 2026
$9.3M
Connecting mGluR and cAMP in the pre-clinical model of Fragile XR01MH093445 · NIMH · MICHIGAN STATE UNIVERSITY · PI WANG, HONGBING · 2012 to 2016
$1.9M
RISK MANAGEMENT IN NATIVE AMERICAN COMMUNITIESR25ES007255 · NIEHS · CLARK UNIVERSITY (WORCESTER, MA) · PI GOBLE, ROBERT L · 1994 to 2002
$738k
NIEHS NIH HHS R25 ES007255NIEHS NIH HHS T32 ES007255NIMH NIH HHS R01 MH093445
6 · The paper itself

Abstract

The temporally dissociated passive avoidance (TDPA) paradigm is a variant of passive avoidance testing, and allows for more sensitive investigation of mild impairments in avoidance learning. Passive avoidance learning measures the latency to enter a "dark" context in which an aversive stimulus (foot shock) has been previously experienced using a light-dark box paradigm. Briefly, the animal is placed into the light side of the box and the time spent to cross into the dark side is measured. After entry into the dark chamber, the animal receives a mild (0.4-1.6 mA) footshock and is removed from the box. After a period of time, typically 24 h (note that this is entirely dependent on whether various levels of memory retention,

Identifiers

PMID29119127
PMCPMC5672628
OpenAlexW2524512063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.