SynthesisJournal of diabetes research2017
Diagnostic Accuracy of Monofilament Tests for Detecting Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis.
Synthesis in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Supersonic shear wave imaging of the tibial nerve for diagnosis of diabetic peripheral neuropathy: A meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Reliability of recommended non-invasive chairside screening tests for diabetes-related peripheral neuropathy: a systematic review with meta-analyses.BMJ open diabetes research & care · 2021Pooled it
- The effectiveness of eye tracking in the diagnosis of cognitive disorders: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review.Medicine · 2019Pooled it
- Correlation Analysis and Intervention Study on Disturbance of Lipid Metabolism and Diabetic Peripheral Neuropathy.Computational and mathematical methods in medicine · 2022Trial
- Diabetic Peripheral Neuropathy: Current Epidemiology, Diagnostic Advances, Biomarkers, and Management Strategies.Journal of diabetes research · 2026Review
- Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives.Drugs & aging · 2026Review
- AI-Powered Thermography for Diabetic Foot Risk Stratification: Multicenter Cross-Sectional Study.JMIR formative research · 2025Article
- Prevalence of Peripheral Neuropathy Among Very Old Adults: Evidence From the Michigan Neuropathy Screening Instrument.Journal of the American Geriatrics Society · 2025Article
- Article
- Racial and Ethnic Differences in Peripheral Neuropathy Risk Factors Among United States Adults.Neurology · 2025Article
- Advanced Dynamic Centre of Pressure Diagnostics with Smart Insoles: Comparison of Diabetic and Healthy Persons for Diagnosing Diabetic Peripheral Neuropathy.Bioengineering (Basel, Switzerland) · 2024Article
- Enhancing diabetic foot ulcer prediction with machine learning: A focus on Localized examinations.Heliyon · 2024Article
- Calibration and Modeling of the Semmes-Weinstein Monofilament for Diabetic Foot Management.Bioengineering (Basel, Switzerland) · 2024Article
- Evaluating and mapping the evidence that screening for diabetic foot disease meets the criteria for population-wide screening: a scoping review.BMJ public health · 2024Article
- Diagnostic Accuracy of Screening Tests for Diabetic Peripheral Neuropathy: An Umbrella Review.Journal of diabetes research · 2024Review
- Development of a transformer-based deep learning algorithm for diabetic peripheral neuropathy classification using corneal confocal microscopy images.Frontiers in cell and developmental biology · 2024Article
- Sympathetic skin response for early detection of type 2 diabetic peripheral neuropathy and nephropathy.Journal of diabetes investigation · 2024Article
- Metformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway.Archives of endocrinology and metabolism · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically evaluate the diagnostic accuracy of monofilament tests for detecting diabetic peripheral neuropathy.
methodsWe searched EMBASE (OvidSP), MEDLINE (OvidSP), the Cochrane Library, and Web of Science to identify diagnostic accuracy trials of monofilament tests for detecting diabetic peripheral neuropathy. We used a hierarchical summary receiver operating characteristics (HSROC) model to conduct the meta-analysis of diagnostic accuracy of monofilament tests for detecting diabetic peripheral neuropathy.
resultsA total of 19 comparative trials met the inclusion criteria and were part of the qualitative synthesis. Eight trials using nerve conduction studies as the reference standard were selected for the meta-analysis. The pooled sensitivity and specificity of monofilament tests for detecting diabetic peripheral neuropathy were 0.53 (95% confidence interval (CI) 0.32 to 0.74) and 0.88 (95% CI 0.78 to 0.94), respectively. The pooled positive likelihood ratio and negative likelihood ratio were 4.56 (95% CI 2.93 to 7.10) and 0.53 (95% CI 0.35 to 0.81), respectively.
conclusionsOur review indicated that monofilament tests had limited sensitivity for screening diabetic peripheral neuropathy. The clinical use of the monofilament test in the evaluation of diabetic peripheral neuropathy cannot be encouraged based on currently available evidence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.