Evidence map›Paper›PMID 29119027›Full record

ArticleCase reports in critical care2017

Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient.

Jana Lass, Kadri Tamme, Karin Kipper, Joel Starkopf

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jana LassTartu University Hospital Pharmacy, Tartu, Estonia.ORCID 0000-0002-3018-3843
Kadri TammeClinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Karin KipperInstitute of Chemistry, University of Tartu, Tartu, Estonia.ORCID 0000-0002-7295-8993
Joel StarkopfClinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.ORCID 0000-0003-4321-3287
Tartu University Hospital · EESt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited available data for dosing in obesity of the medicines used in this case are discussed, with the emphasis on ertapenem. The case illustrates the difficulties in dosing medicines to morbidly overweight patients. The number of such patients is increasing but data on adequate doses of medicines are scarce. We demonstrate that ertapenem 1,5 g i.v. once daily provided adequate drug exposure for susceptible bacteria in a 250 kg patient with normal renal function. The case suggests the usefulness of therapeutic drug monitoring of antibiotics, especially in critically ill patients.

Identifiers

PMID29119027
PMCPMC5651098
OpenAlexW2761720048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.